Differentiated neuroblastoma cells (SH-SY5Y) were used to study the effects of lowstatic magnetic fields (SMFs) and extremely low frequency electromagnetic fields (ELF-EMFs) on the structure of DNA. Fourier Transform Infrared (FTIR) spectroscopy analysis showed that exposures to a SMF at 2mT and to a 50Hz EMF at 0.7mT produced peak s centroid shift and significant decreases of the phosphate absorption bands in the infrared region of DNA. The exposure also induced significant increase in reactive oxygen species (ROS) production in comparison to control confirming this scenario.

Electromagnetic fields low levels altered the DNA infrared region in RA-differentiated SH-SY5Y neuroblastoma cells

CALABRO', EMANUELE;MAGAZU', Salvatore;IENTILE, Riccardo
2012-01-01

Abstract

Differentiated neuroblastoma cells (SH-SY5Y) were used to study the effects of lowstatic magnetic fields (SMFs) and extremely low frequency electromagnetic fields (ELF-EMFs) on the structure of DNA. Fourier Transform Infrared (FTIR) spectroscopy analysis showed that exposures to a SMF at 2mT and to a 50Hz EMF at 0.7mT produced peak s centroid shift and significant decreases of the phosphate absorption bands in the infrared region of DNA. The exposure also induced significant increase in reactive oxygen species (ROS) production in comparison to control confirming this scenario.
2012
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/2489422
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