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EnglishAIM: The need for early markers of atherosclerosis in paediatric ages has been emphasized recently. Few data are available on the behaviour of carotid intima-media thickness (cIMT) and arterial stiffness in normal children. METHODS: We studied prospectively 131 healthy children (78 boys), aged 3-16 years, by high-definition ultrasonography and echo-tracking technique in order to evaluate cIMT and stiffness index β. RESULTS: Stiffness index β underwent a significant age-related increase (P < 0.001), and a positive relationship between cIMT and height was found in boys. In addition, stiffness index β and cIMT were not related to each other (P = 0.97). CONCLUSION: This study provides information about two markers of subclinical atherosclerosis, cIMT and carotid stiffness index β, in normal children aged 3-16 years. We found a significant age-related and height-related increase of stiffness index β in both sexes, whereas cIMT was positively related to height only in boys.
| Titolo: | Carotid artery intima-media thickness and stiffness index β changes in normal children: role of age, height and sex |
| Autori: | CALABRO', Maria Pia (Primo) ORETO, Giuseppe (Ultimo) |
| Data di pubblicazione: | 2015 |
| Rivista: | |
| Abstract: | AIM: The need for early markers of atherosclerosis in paediatric ages has been emphasized recently. Few data are available on the behaviour of carotid intima-media thickness (cIMT) and arterial stiffness in normal children. METHODS: We studied prospectively 131 healthy children (78 boys), aged 3-16 years, by high-definition ultrasonography and echo-tracking technique in order to evaluate cIMT and stiffness index β. RESULTS: Stiffness index β underwent a significant age-related increase (P < 0.001), and a positive relationship between cIMT and height was found in boys. In addition, stiffness index β and cIMT were not related to each other (P = 0.97). CONCLUSION: This study provides information about two markers of subclinical atherosclerosis, cIMT and carotid stiffness index β, in normal children aged 3-16 years. We found a significant age-related and height-related increase of stiffness index β in both sexes, whereas cIMT was positively related to height only in boys. |
| Handle: | http://hdl.handle.net/11570/3065054 |
| Appare nelle tipologie: | 14.a.1 Articolo su rivista |
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