The neural mechanisms underlying fatigue in multiple sclerosis (MS) are still poorly understood. Cortico-cortical and cortico-subcortical circuitry abnormalities may play a central role in its pathogenesis. Our previous studies suggest that central fatigue may be related to an impairment of volition drive during movement preparation.
Fatigue in patients with multiple sclerosis: from movement preparation to motor execution
RUSSO, MARGHERITA
Primo
;CRUPI, domenica;NARO, ANTONINO;BUCCAFUSCA, MARIA;DATTOLA, VINCENZO;TERRANOVA, CARMEN;SOTTILE, FABRIZIO;RIZZO, VINCENZO;GIRLANDA, Paolo;QUARTARONE, AngeloUltimo
2015-01-01
Abstract
The neural mechanisms underlying fatigue in multiple sclerosis (MS) are still poorly understood. Cortico-cortical and cortico-subcortical circuitry abnormalities may play a central role in its pathogenesis. Our previous studies suggest that central fatigue may be related to an impairment of volition drive during movement preparation.File in questo prodotto:
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