Thyroid gland metastasis from breast cancer as sixth site of disease:A Case Report

Intra-thyroid metastases are uncommon in clinical practice. Although, the possibility of a metastasis from non-thyroid cancers to the thyroid gland is rare it should be taken into account, because it is not as infrequent as widely believed. Thyroid metastases are not frequent in breast cancer, but a new thyroid mass should be considered as a metastasis of breast carcinoma in any patient with a former history of this malignancy. Breast metastatic cancer is valuated at ca.16.0 to 32.0% in postmortem examinations, but only 4.0-9.0% cases are encountered in clinical papers. We report a case of metastatic lesion in the thyroid from breast carcinoma, already metastasized in five other locations, recognized in a fine-needle aspiration (FNAB) biopsy followed by istopathological confirmation and immunohistochemical examination.