Intrathecal administration of baclofen (ITB) is widely recognized as an effective treatment for severe spasticity of both spinal and supraspinal origin with fewer side effects. The lower drug dosages used for spinal intrathecal administration, acting directly on the receptor sites, result in greater therapeutic efficacy with less systemic toxicity than with oral preparations.
Sexual dysfunction induced by intrathecal baclofen administration: is this the price to pay for severe spasticity management?
CALABRO', ROCCO SALVATORE;D'ALEO, GIANGAETANO;SESSA, Edoardo;BRAMANTI, Placido
2014-01-01
Abstract
Intrathecal administration of baclofen (ITB) is widely recognized as an effective treatment for severe spasticity of both spinal and supraspinal origin with fewer side effects. The lower drug dosages used for spinal intrathecal administration, acting directly on the receptor sites, result in greater therapeutic efficacy with less systemic toxicity than with oral preparations.File in questo prodotto:
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