Use of collagen matrix to improve wound repair after mucosal biopsy: a multicenter case series

Oral soft tissue lesions are commonly seen in the daily dental practice. The quick diagnosis of oral poten- tially malignant disorders and oral precancer disease is of highest clinical importance given the mortality rate of late stage disease. Since the oral cavity is more accessible to complete examination, it could be used in early detection of precancerous and cancerous lesions. But either due to ignorance or inaccessibility of medical care, the disease gets detected in the later stages. Thus, there is a need for improvement in early detection of oral disease, because in the initial stages, treatment is more effective and the morbidity is minimal. Aim of this report is to highlight how collagen membrane graft application seems to offer a perfect healing of the soft tissue after the lesion removal. Some reports and the microstructure of the collagen used have been recorded. The healing of the soft tissue, the bleeding control and the management of postoperative discomfort seem to be more favorable by avoiding a intra- oral soft tissue graft and applying a collagen membrane.