Amphiphilic PEGylated calix[5]arenes 1 and 2 were obtained in one step from the parent p-tertbutylcalix[ 5]arene and p-methylcalix[5]arene. Very low critical micellar concentrations (0.5 and 4.5 μM for 1 and 2 respectively) were determined by the Rose Bengal micellization method. Aggregation features were studied by means of 1H and DOSY NMR as well as by AFM. Release of Rose Bengal from the micellar environment was accomplished by increasing the temperature.
Novel PEGylated calix[5]arenes as carriers for Rose Bengal
I. Pisagatti;L. Barbera;G. Gattuso;S. Patanè;M. F. Parisi;A. Notti
2018-01-01
Abstract
Amphiphilic PEGylated calix[5]arenes 1 and 2 were obtained in one step from the parent p-tertbutylcalix[ 5]arene and p-methylcalix[5]arene. Very low critical micellar concentrations (0.5 and 4.5 μM for 1 and 2 respectively) were determined by the Rose Bengal micellization method. Aggregation features were studied by means of 1H and DOSY NMR as well as by AFM. Release of Rose Bengal from the micellar environment was accomplished by increasing the temperature.File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
