Celiac disease is caused by a specific immune response to antigens present in wheat gluten and related proteins of rye and barley in genetically susceptible individuals. Several studies have been conducted to define the nature and role of systemic cytokine levels in the pathophysiology of celiac disease. In order to identify the potential role of the Th17 subset in the pathogenesis of the celiac disease, we analyzed the serum levels of IL -22 in affected patients. Our data show that higher IL -22 serum levels are found in cases than in the controls, with a difference near to the limits of significance.
Is IL-22 involved in celiac disease?
IMBESI, SELENE CARMELA;Ferraro, Martina;Mannucci;S. Gangemi
2013-01-01
Abstract
Celiac disease is caused by a specific immune response to antigens present in wheat gluten and related proteins of rye and barley in genetically susceptible individuals. Several studies have been conducted to define the nature and role of systemic cytokine levels in the pathophysiology of celiac disease. In order to identify the potential role of the Th17 subset in the pathogenesis of the celiac disease, we analyzed the serum levels of IL -22 in affected patients. Our data show that higher IL -22 serum levels are found in cases than in the controls, with a difference near to the limits of significance.File in questo prodotto:
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