Patients with human immunodeficiency virus (HIV) infection have a higher risk of low bone mineral density (BMD) and fragility fracture than the general population, although the etiological mechanisms are poorly known. The aim of this review is to summarize the available literature data about alterations of bone metabolism in HIV-infected patients to assess the impact of HIV infection and highly active antiretroviral therapy (HAART) on the risk of developing osteopenia and osteoporosis and to provide guidance on the screening, diagnosis, and monitoring of bone disease in HIV-positive population.

Bone disease in HIV infection: an overview of pathogenesis, clinical manifestations and treatment

F. D’Andrea;A. Facciolà;E. Venanzi Rullo;G. Visalli;G. F. Pellicanò
Ultimo
2019

Abstract

Patients with human immunodeficiency virus (HIV) infection have a higher risk of low bone mineral density (BMD) and fragility fracture than the general population, although the etiological mechanisms are poorly known. The aim of this review is to summarize the available literature data about alterations of bone metabolism in HIV-infected patients to assess the impact of HIV infection and highly active antiretroviral therapy (HAART) on the risk of developing osteopenia and osteoporosis and to provide guidance on the screening, diagnosis, and monitoring of bone disease in HIV-positive population.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/3148340
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