Oral anticoagulation is a milestone in the management of atrial fibrillation (AF). In complex settings, involving some kinds of thrombophilia, a condition predisposing to higher risk of thromboembolism, warfarin can be ineffective. Direct oral anticoagulants (DOACs) demonstrated to be a valid therapeutic option; in particular edoxaban proved to be effective and safe. We show the case of a man with AF and thrombophilia who developed a thrombus in the left atrial appendage (LAA) despite anticoagulant therapy with warfarin, subsequently treated with edoxaban.

Atrial fibrillation and thrombophilia. DOAC as a valid alternative? A clinical case

Claudia Morabito
Primo
Investigation
;
Pasquale Crea
Investigation
;
Luca Zappia
Investigation
;
Roberto Licordari
Investigation
;
Alessandro Migliorato
Investigation
;
Francesco Luzza
Penultimo
Investigation
;
Giuseppe Dattilo
Ultimo
Supervision
2020-01-01

Abstract

Oral anticoagulation is a milestone in the management of atrial fibrillation (AF). In complex settings, involving some kinds of thrombophilia, a condition predisposing to higher risk of thromboembolism, warfarin can be ineffective. Direct oral anticoagulants (DOACs) demonstrated to be a valid therapeutic option; in particular edoxaban proved to be effective and safe. We show the case of a man with AF and thrombophilia who developed a thrombus in the left atrial appendage (LAA) despite anticoagulant therapy with warfarin, subsequently treated with edoxaban.
2020
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/3181432
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