Heart failure is a major public health concern, being one of the most common reasons for hospitalization. Its prognosis is poor and the optimal management to date represents a continuous challenge. This case report describes a 67-year-old man with chronic heart failure with reduced ejection fraction (HFrEF), remaining symptomatic despite optimal medical therapy and refusing an implantable cardioverter-defibrillator (ICD) as a prevention for sudden cardiac death. We introduced Sacubitril/Valsartan and after 3 months of treatment we observed a significant improvement in symptoms with reduction of arrhythmic burden and, after six months even of echocardiographic parameters, leading to withdraw the indication to the ICD.

Sacubitril/Valsartan and implantable cardioverter-defibrillators: evolving therapeutic strategies. A case report

Claudia Morabito
Primo
Investigation
;
Marianna Gigliotti De Fazio
Secondo
Investigation
;
Giuseppe Dattilo
Penultimo
Supervision
;
2020

Abstract

Heart failure is a major public health concern, being one of the most common reasons for hospitalization. Its prognosis is poor and the optimal management to date represents a continuous challenge. This case report describes a 67-year-old man with chronic heart failure with reduced ejection fraction (HFrEF), remaining symptomatic despite optimal medical therapy and refusing an implantable cardioverter-defibrillator (ICD) as a prevention for sudden cardiac death. We introduced Sacubitril/Valsartan and after 3 months of treatment we observed a significant improvement in symptoms with reduction of arrhythmic burden and, after six months even of echocardiographic parameters, leading to withdraw the indication to the ICD.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11570/3181434
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