Leydig-Sertoli collision sex-cord stromal tumor of the testis: a case report of an unusual entity

Testicular tumors are extremely rare, representing 1–1.5% of all neoplasms in men, and sex cord-stromal tumors account for about 5% of them. Histopathological diagnosis of such entities poses several challenges, mainly related to the fact that they can present in mixed forms and that immunohistochemical analyses can only be of partial help. We herein report a unique case of a collision sex cord-stromal tumor and discuss all the challenges faced in the diagnosis of such an entity. An accurate morphological examination of the entire lesion and a suitable immunohistochemical panel are essential for a correct diagnosis.