Can crayfish serve as bioindicator of environmental impact after exposure to Bisphenol A?

: Bisphenol-A (BPA), is one of the industrial chemicals used mainly in the production of polycarbonates and epoxy resins, also known as endocrine disruptor and contaminant in aquatic ecosystems. Therefore, the present study aimed to determine the sublethal effects of BPA on the narrow-clawed crayfish, in terms of haemolymph parameters and histopathological changes after 24 and 96 h exposure times. The study was conducted in semi-static bioassays with 1.14 and 0.114 mg/L BPA concentrations. The total haemocyte counts significantly decreased in the 24 h exposed to BPA (p < 0.05). The lactate, glucose, and calcium values of haemolymph were significantly increased in the BPA-exposed groups (p < 0.05). The gills and the hepatopancreas tissues of the species revealed histopathological alterations at 1.14 mg/L following exposure to BPA in both exposure durations. The results of the study showed that the BPA can affect the health status of aquatic organisms via physiology and histopathology even at sublethal levels at acute exposure times.