A new ring opening reaction of isoxazolidine nucleus is reported, which is based on the treatment of 3-carboxyalkyl-substituted derivatives with NaH. The process results in a new and general synthetic pathway towards the formation of 3-methylamino-2(5H)furanones.
Ring-opening of the isoxazolidine system: a new synthesis of 2-amino-5H-furanones
ROMEO, Giovanni;ROMEO, Roberto;
1995-01-01
Abstract
A new ring opening reaction of isoxazolidine nucleus is reported, which is based on the treatment of 3-carboxyalkyl-substituted derivatives with NaH. The process results in a new and general synthetic pathway towards the formation of 3-methylamino-2(5H)furanones.File in questo prodotto:
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