The 1,3-dipolar cycloaddition of vinyloxymethyl thymine with different nitrones has been exploited for the preparation of N,O-homonucleosides where the oxymethylene tether replaces the aminal linkage between the sugar moiety and the nucleobase
SYNTHESIS OF N,O-HOMO-NUCLEOSIDES WITH HIGH CONFORMATIONAL FREEDOM
ROMEO, Giovanni;GIOFRE', Salvatore Vincenzo;PIPERNO, Anna;ROMEO, Roberto;
2009-01-01
Abstract
The 1,3-dipolar cycloaddition of vinyloxymethyl thymine with different nitrones has been exploited for the preparation of N,O-homonucleosides where the oxymethylene tether replaces the aminal linkage between the sugar moiety and the nucleobaseFile in questo prodotto:
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