Mild carbohydrate intolerance in pregnancy

Abstract Diagnosis of Gestational Diabetes Mellitus (GDM) requires at least two or more values to be abnormal on the 3 h-100 g oral glucose tolerance test: but how to care for pregnant women with only one abnormal glucose value remains a point of discussion. In fact, although a large number of studies on this argument exist, the clinical significance of "one abnormal value" has yet to be clarified. Our review of previous studies and personal experience on prevalence, metabolic findings and maternal-fetal outcome suggests this pregnancy induced carbohydrate intolerance is a continuum with GDM, associated with an increased incidence of materno-fetal complications. For this reason we believe that it should be diagnosed, monitored and treated.