Post-operative Radiotherapy of keloids. A 10-years experience of kilovoltage irradiation.

Pontoriero, A.; Potami, A.; Iatì, G.; Comitini, S.; Venza, M.; Settineri, N.; Pergolizzi, S.; De Renzis, C.

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Background. Keloids are benign fibrous dermal tumors originating from skin injury after surgery, piercing or others wounds. Aims. To evaluate the role of post-operative superficial orthovoltage radiotherapy in the management of keloids. Methods. Sixty-two patients with keloids were treated postoperatively using orthovoltage irradiation. The total dose delivered was 12 Gy in three consecutive days, 4Gy per fraction. Treatment started 24 h after surgery. The median follow-up was 44,5 months. Results. Grade 1 erythema was observed in 48% of patients (30/62); 20/62 patients (32%) showed telangiectasias and altered skin pigmentation as late toxicities. In 10/62 (16%) a clinical relapse was observed. Conclusions. The postoperative orthovoltage radiotherapy for keloids is a valid and tolerated method that reduces the risk of recurrence.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11570/3011174

Titolo:	Post-operative Radiotherapy of keloids. A 10-years experience of kilovoltage irradiation.
Autori interni:	PONTORIERO, ANTONIO VENZA, Mario PERGOLIZZI, Stefano DE RENZIS, Costantino
Data di pubblicazione:	2015
Rivista:	IRANIAN JOURNAL OF RADIATION RESEARCH
Abstract:	Background. Keloids are benign fibrous dermal tumors originating from skin injury after surgery, piercing or others wounds. Aims. To evaluate the role of post-operative superficial orthovoltage radiotherapy in the management of keloids. Methods. Sixty-two patients with keloids were treated postoperatively using orthovoltage irradiation. The total dose delivered was 12 Gy in three consecutive days, 4Gy per fraction. Treatment started 24 h after surgery. The median follow-up was 44,5 months. Results. Grade 1 erythema was observed in 48% of patients (30/62); 20/62 patients (32%) showed telangiectasias and altered skin pigmentation as late toxicities. In 10/62 (16%) a clinical relapse was observed. Conclusions. The postoperative orthovoltage radiotherapy for keloids is a valid and tolerated method that reduces the risk of recurrence.
Handle:	http://hdl.handle.net/11570/3011174
Appare nelle tipologie:	14.a.1 Articolo su rivista

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