Coal tar is a complex mixture of organic compounds obtained from the thermal treatment of coal; it contains several different chemical classes of compounds, such as polycyclic aromatic hydrocarbons, phenols and different heterocyclic compounds including sulphur derivatives. In the present research, a target analysis was carried out for the characterisation of fourteen different classes of organic sulphur compounds in coal tar by using cryogenically-modulated (CM) comprehensive two-dimensional gas chromatography-high resolution time-of-flight mass spectrometry (GC×GC-HR ToFMS) with the support of target analyte finding, a specific software function. Furthermore, absolute quantification data were obtained by using eight pure standard sulphur compounds, and 1-fluoronaphthalene as internal standard. Several figures-of-merit of the proposed method were measured (linearity, intra-day precision, limits of detection and quantification). Finally, the overall analytical performance of CM GC×GC-HR ToFMS was evaluated, in relation to MS similarities, mass accuracies, second-dimension peak widths, peak capacity and tailing factors. The approach proved itself as being a powerful analytical platform, benefiting from the high sensitivity, selectivity and resolving power, of both the GC and MS sides.

Analysis of organic sulphur compounds in coal tar by using comprehensive two-dimensional gas chromatography-high resolution time-of-flight mass spectrometry

Aloisi I.
Primo
;
Zoccali M.
Secondo
;
Tranchida P. Q.
Penultimo
;
Mondello L.
Ultimo
2020

Abstract

Coal tar is a complex mixture of organic compounds obtained from the thermal treatment of coal; it contains several different chemical classes of compounds, such as polycyclic aromatic hydrocarbons, phenols and different heterocyclic compounds including sulphur derivatives. In the present research, a target analysis was carried out for the characterisation of fourteen different classes of organic sulphur compounds in coal tar by using cryogenically-modulated (CM) comprehensive two-dimensional gas chromatography-high resolution time-of-flight mass spectrometry (GC×GC-HR ToFMS) with the support of target analyte finding, a specific software function. Furthermore, absolute quantification data were obtained by using eight pure standard sulphur compounds, and 1-fluoronaphthalene as internal standard. Several figures-of-merit of the proposed method were measured (linearity, intra-day precision, limits of detection and quantification). Finally, the overall analytical performance of CM GC×GC-HR ToFMS was evaluated, in relation to MS similarities, mass accuracies, second-dimension peak widths, peak capacity and tailing factors. The approach proved itself as being a powerful analytical platform, benefiting from the high sensitivity, selectivity and resolving power, of both the GC and MS sides.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/3168492
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