Sirtuins comprise seven family elements (SIRT1-7) involved in various cell signalling pathways comprising cancer inhibition and tumorigenesis. The present study aims to evaluate SIRT2 and SIRT3 gene expression and potential redox reactions in patients with multiple myeloma (MM) at onset and its correlation with disease status, extent and presence of organ damage secondary to myeloma.

SIRT2 and SIRT3 expression correlates with redox imbalance and advanced clinical stage in patients with multiple myeloma

Allegra, Alessandro
Primo
Writing – Original Draft Preparation
;
Innao, Vanessa
Resources
;
Polito, Francesca
Investigation
;
Oteri, Rosaria
Validation
;
Alibrandi, Angela
Formal Analysis
;
Oteri, Giacomo
Supervision
;
Di Giorgio, Rosa Maria
Methodology
;
Musolino, Caterina
Penultimo
Project Administration
;
Aguennouz, M'hammed
Ultimo
Conceptualization
2021-01-01

Abstract

Sirtuins comprise seven family elements (SIRT1-7) involved in various cell signalling pathways comprising cancer inhibition and tumorigenesis. The present study aims to evaluate SIRT2 and SIRT3 gene expression and potential redox reactions in patients with multiple myeloma (MM) at onset and its correlation with disease status, extent and presence of organ damage secondary to myeloma.
2021
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/3203304
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