IRIS
MICALE, Nicola
 Distribuzione geografica
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Continente #
NA - Nord America 3.141
EU - Europa 2.997
AS - Asia 609
Continente sconosciuto - Info sul continente non disponibili 8
SA - Sud America 6
AF - Africa 3
OC - Oceania 2
Totale 6.766
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Nazione #
US - Stati Uniti d'America 3.128
IE - Irlanda 1.047
SE - Svezia 780
CN - Cina 422
IT - Italia 317
UA - Ucraina 295
DE - Germania 197
FI - Finlandia 128
GB - Regno Unito 99
VN - Vietnam 73
SG - Singapore 53
IN - India 49
PL - Polonia 36
CZ - Repubblica Ceca 31
RU - Federazione Russa 23
BE - Belgio 17
CA - Canada 10
EU - Europa 7
AT - Austria 6
ES - Italia 4
NL - Olanda 4
CL - Cile 3
FR - Francia 3
IR - Iran 3
LV - Lettonia 3
ZA - Sudafrica 3
BR - Brasile 2
ID - Indonesia 2
JP - Giappone 2
MX - Messico 2
PT - Portogallo 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AU - Australia 1
BD - Bangladesh 1
BG - Bulgaria 1
CH - Svizzera 1
DK - Danimarca 1
EC - Ecuador 1
EE - Estonia 1
HU - Ungheria 1
IL - Israele 1
IQ - Iraq 1
NZ - Nuova Zelanda 1
PA - Panama 1
TH - Thailandia 1
TR - Turchia 1
Totale 6.766
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Città #
Dublin 1.046
Jacksonville 596
Chandler 560
Nyköping 529
Beijing 215
Ashburn 200
Princeton 163
Medford 136
Cambridge 126
Dearborn 121
Messina 118
Des Moines 107
Boardman 76
Ann Arbor 73
Dong Ket 72
Lancaster 38
Warsaw 36
Jinan 35
Woodbridge 31
Wilmington 30
Singapore 29
San Mateo 23
Shenyang 23
Brno 22
Pune 21
Nanjing 19
Brussels 16
Seattle 16
Hyderabad 15
Rome 14
Norwalk 13
Tianjin 13
Milan 12
New York 11
Hebei 10
Nanchang 10
Augusta 9
Munich 9
Taizhou 9
Zhengzhou 9
Clearwater 8
Haikou 8
Hangzhou 8
Houston 8
Ningbo 8
Olomouc 8
Francofonte 7
Los Angeles 6
Ottawa 6
Vienna 6
Auburn Hills 5
Bologna 5
Bonn 5
Fuzhou 5
Jiaxing 5
Padova 5
Reggio Calabria 4
Saint Petersburg 4
Siracusa 4
Taiyuan 4
Cape Town 3
Chicago 3
Guangzhou 3
Hefei 3
Helsinki 3
Lanzhou 3
Las Vegas 3
Leawood 3
Madrid 3
Richmond 3
Sevastopol 3
Tappahannock 3
Washington 3
Amsterdam 2
Ardabil 2
Bandung 2
Borghetto Santo Spirito 2
Boston 2
Camisano Vicentino 2
Catania 2
Changsha 2
Cosenza 2
Fiorenzuola D'arda 2
Groningen 2
Kemerovo 2
Kunming 2
London 2
Marche 2
Montréal 2
Napoli 2
New Delhi 2
Pedara 2
Perugia 2
Ragusa 2
Riva 2
Saint Louis 2
San Gavino Monreale 2
Shanghai 2
Acate 1
Almada 1
Totale 4.821
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Nome #
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 131
Polimorfismi del gene PON1, attività della paraoxonase sierica ed effetti antiossidanti dell’atorvastatina in soggetti del sud Italia 102
Antimicrobial peptide capsids of de novo design 84
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 78
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 74
Silibinin-conjugated graphene nanoplatform: Synthesis, characterization and biological evaluation 70
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 69
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 69
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 68
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 67
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 67
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 67
Design, synthesis and biological evaluation of peptidomimetics boronic acids targeting 20S proteasome 62
5-Phenyl-9H-1,3-dioxolo[4,5-h][2,3]-benzodiazepin-8(7H)-one 61
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 60
STRATEGIES FOR SYNTHESIS OF CONFORMATIONALLY CONSTRAINED GLUTAMATE ANALOGUES 60
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 60
Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors 60
Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE 60
Antimicrobial and antiprotozoal activities of silver coordination polymers derived from the asymmetric halogenated Schiff base ligands 60
Synthesis and anticonvulsant activity of novel and potent 6,7- methylenedioxyphthalazin-1(2H)-ones 59
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 59
"Click" on PLGA-PEG and hyaluronic acid: Gaining access to anti-leishmanial pentamidine bioconjugates 59
N-Hydroxypyrazolyl Glycine Derivatives as Selective N-Methyl-D-aspartic Acid Receptor Ligands 58
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 58
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 56
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 56
Falcipain-2 inhibitors 56
DEVELOPMENT OF NOVEL PEPTIDOMIMETICS CONTAINIG A VINYL SULFONE MOIETY AS PROTEASOME INHIBITORS 56
A hyaluronic acid–pentamidine bioconjugate as a macrophage mediated drug targeting delivery system for the treatment of leishmaniasis 56
Novel potent AMPA/kainate receptor antagonists: Synthesis and anticonvulsant activity of a series of 2-[(4- alkylsemicarbazono)-(4-aminophenyl)methyl]-4,5- methylenedioxyphenylacetic acid alkyl esters 55
Synthesis and anticonvulsant activity of novel and potent 1- aryl-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3- benzodiazepin-4-ones 55
Development of nonpeptidic vinyl and allyl phosphonates as active-site-directed inhibitors of falcipain-2 55
Chloro-substituted Hoveyda-Grubbs ruthenium carbene: investigation of electronic effects 55
Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: The Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives 55
Synthesis and anticonvulsant activity of novel and potent 2,3- benzodiazepine AMPA/kainate receptor antagonists 54
Subunit-specific agonist activity at NR2A, NR2B, NR2C, and NR2D containing N-methyl-D-aspartate glutamate receptors. 54
Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist 54
Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents 53
Chloro-substituted Hoveyda-Grubbs ruthenium carbene: Investigation of electronic effects 53
Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: identification of the 1-(4-amino,3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent 53
Characterization of the binding site in a series of AMPA receptor antagonists. 53
Synthesis of C3/C1-Substituted Tetrahydroisoquinolines 53
Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors 52
Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain 52
Synthesis of 5-substituted 7,9-dihydro-8H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-8-ones as anticonvulsant agents 51
Novel peptidomimetic cysteine protease inhibitors as potential antimalarial agents 51
Synthesis, chiral resolution and enantiopharmacology of a potent 2,3-benzodiazepine as noncompetitive AMPA receptor antagonist 51
Development of Peptidomimetics with a Vinyl Sulfone Warhead as Irreversible Falcipain-2 Inhibitors 51
Progettazione e sintesi di nuovi antagonisti noncompetitivi del recettore AMPA 51
Synthesis and in vitro antitumour activity evaluation of 1-aryl-1H,3H-thiazolo[4,3-b]-quinazolines 50
PREPARATION OF PLA-BASED NANOPARTICLES LOADED WITH SALINOMYCIN AND FOLIC ACID 50
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis 50
Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Bearing a Pyrazole Scaffold and a Cinnamoyl Linker 50
Characterization of the mechanism of anticonvulsant activity for a selected set of putative AMPA receptor antagonists 49
Synthesis of Nanoterapeutics based on G/HA platforms for osteosarcoma targeting. 49
Fluorine-based pseudopeptides from halocarbene transfer reaction: synthesis and biological perspectives 49
Synthesis and anticonvulsant activity of new 2,3-benzodiazepines as AMPA receptor antagonists 48
Structure-activity relationships of 2,3-benzodiazepines as AMPA/KA receptor antagonists 48
New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists 48
Synthesis and anti-HIV activity evaluation of new phenyl ethyl thiourea (PET) derivatives 48
Synthesis of Peptidomimetics with the Benzodiazepine Nucleus as beta-turn mimic 47
Structure-activity relationships of 2,3-benzodiazepines as AMPA/KA receptor antagonists. 47
Glutamate Binding-Site Ligands of NMDA Receptors 47
6,7-Methylenedioxyphthalazin-1(2H)-ones as novel and potent anticonvulsant agents 47
Synthesis and structure-activity relationship of 2,3-benzodiazepines AMPA receptor antagonists 47
Synthesis and antitumor activity of 1,3-benzodioxole derivatives 46
Reazioni di cross metathesis: applicazione alla sintesi di peptidomimetici potenziali inibitori di falcipaina-2 46
6,7-Methylenedioxyquinazolin-4-ones as Anticonvulsant Agents 46
Synthesis of benzothiazole derivatives and their biological evaluation as anticancer agents 46
4,5-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 45
Nuovi derivati dell’acido 4,5-metilendiossi-fenilacetico antagonisti del recettore AMPA/KA. 45
Novel peptidomimetics as antiplasmodial falcipain-2 inhibitors 45
Synthesis and cytotoxic activity of 1,3-benzodioxole derivatives. Note II 44
Novel 2H-Isoquinolin-3-ones Falcipain-2 Inhibitors as Antimalarial Agents 44
Development of peptidomimetic boronates as proteasome inhibitors 44
Synthesis of Peptidomimetics with the Benzodiazepine Nucleus as beta-turn mimic 44
Hydrogels for the Delivery of Plant-Derived (Poly)Phenols 44
Peptide-based α,α-Difluoromethyl Ketone as new inhibitor of Pathogenic Coronavirus Mpro 44
Anticancer study of heterobimetallic platinum(II)-ruthenium(II) and platinum(II)-rhodium(III) complexes with bridging dithiooxamide ligand 44
Design of 1-substituted 2-arylmethyl-4,5-methylenedioxybenzene derivatives as antiseizure agents 43
Enantioseparazione, determinazione della configurazione assoluta ed attività anticonvulsivante dell’1-(4-aminofenil)-1,2,3,5-tetraidro-7,8-metilendiossi-4H-2,3-benzodiazepin-4-one. 43
Targeting of the Leishmania Mexicana cysteine protease CPB2.8 ΔCTE by decorated fused benzo[b] thiophene scaffold. 42
New 2,3-benzodiazepines as noncompetitive AMPA receptor antagonists. 41
Novel peptidomimetic cysteine protease inhibitors as antimalarial agents 41
Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents 41
Progettazione e sintesi di nuovi antagonisti noncompetivi del recettore AMPA 40
Synthesis and anticonvulsant activity of new 2,3- benzodiazepines as AMPA receptor antagonists 40
Mechanism of Inhibition of GluA2 AMPA Receptor Channel Opening by 2,3-Benzodiazepine Derivatives: Functional Consequences of Replacing a 7,8-Methylenedioxy with a 7,8-Ethylenedioxy Moiety 40
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF PEPTIDOMIMETIC FALCIPAIN-2 INHIBITORS AS ANTIMALARIAL AGENTS 40
Silibinin conjugated graphene and hyaluronic acid platforms for osteosarcoma targeting 40
Direct and chemoselective transfer of the difluoromethyl (CHF2) unit into carbon-electrophiles under nucleophilic regime 40
Copper(II) complexes with tridentate halogen‐substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving group and ligand flexibility on antiproliferative activities 40
Design and synthesis of a potent and selective peptidomimetic inhibitor of caspase-3 39
Novel Peptidomimetics Containing a Vinyl Ester Moiety as Highly Potent and Selective Falcipain-2 Inhibitors 39
Synthesis and Molecular Modeling Studies of Derivatives of a Highly Potent Peptidomimetic Vinyl Ester as Falcipain-2 Inhibitors 39
New 4,5-methylenedioxsyphenyl derivatives as AMPA/KA receptor antagonists 38
Development of peptidomimetic boronates as proteasome inhibitors 38
SYNTHESIS OF PYRAZOLE DERIVATIVES DESIGNED AS POTENTIAL INHIBITORS OF DIFFERENT HDAC ISOFORMS 37
Antiproliferative properties of a few auranofin-related gold(I) and silver(I) complexes in leukemia cells and their interferences with the ubiquitin proteasome system 37
Totale 5.262
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Categoria #
all - tutte 28.533
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.533
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020993 162 66 3 68 7 121 134 98 9 148 167 10
2020/2021953 102 11 168 55 66 99 16 83 24 162 57 110
2021/2022978 13 169 15 30 19 4 70 40 7 33 249 329
2022/20232.659 208 196 111 189 173 274 43 121 1.244 12 63 25
2023/2024601 42 84 61 147 65 75 5 31 6 20 10 55
2024/202539 39 0 0 0 0 0 0 0 0 0 0 0
Totale 7.087