IRIS
MICALE, Nicola
 Distribuzione geografica
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Continente #
EU - Europa 5.290
NA - Nord America 5.158
AS - Asia 3.256
SA - Sud America 1.388
AF - Africa 102
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 5
AN - Antartide 1
Totale 15.209
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Nazione #
US - Stati Uniti d'America 5.049
RU - Federazione Russa 1.902
SG - Singapore 1.452
BR - Brasile 1.235
IE - Irlanda 1.043
SE - Svezia 801
CN - Cina 763
HK - Hong Kong 435
IT - Italia 397
UA - Ucraina 313
DE - Germania 262
VN - Vietnam 252
GB - Regno Unito 158
FI - Finlandia 150
IN - India 88
PL - Polonia 70
AR - Argentina 59
CA - Canada 49
ZA - Sudafrica 42
BD - Bangladesh 37
MX - Messico 34
TR - Turchia 33
CZ - Repubblica Ceca 32
ID - Indonesia 31
IQ - Iraq 31
ES - Italia 30
FR - Francia 30
EC - Ecuador 27
BE - Belgio 21
UZ - Uzbekistan 21
JP - Giappone 19
MA - Marocco 18
NL - Olanda 18
CO - Colombia 16
AT - Austria 13
PK - Pakistan 13
TN - Tunisia 13
VE - Venezuela 13
PY - Paraguay 12
AE - Emirati Arabi Uniti 11
AZ - Azerbaigian 10
PE - Perù 10
CL - Cile 7
EU - Europa 7
LT - Lituania 7
NP - Nepal 7
UY - Uruguay 7
DZ - Algeria 6
HN - Honduras 6
IL - Israele 6
DO - Repubblica Dominicana 5
GE - Georgia 5
KE - Kenya 5
OM - Oman 5
AL - Albania 4
BY - Bielorussia 4
CI - Costa d'Avorio 4
HU - Ungheria 4
IR - Iran 4
JM - Giamaica 4
LB - Libano 4
LV - Lettonia 4
PA - Panama 4
RS - Serbia 4
SN - Senegal 4
AM - Armenia 3
CH - Svizzera 3
DK - Danimarca 3
GR - Grecia 3
JO - Giordania 3
MY - Malesia 3
PT - Portogallo 3
SK - Slovacchia (Repubblica Slovacca) 3
TT - Trinidad e Tobago 3
AO - Angola 2
BG - Bulgaria 2
BH - Bahrain 2
BO - Bolivia 2
EE - Estonia 2
ET - Etiopia 2
GT - Guatemala 2
KG - Kirghizistan 2
KZ - Kazakistan 2
LA - Repubblica Popolare Democratica del Laos 2
NZ - Nuova Zelanda 2
PH - Filippine 2
QA - Qatar 2
RO - Romania 2
SA - Arabia Saudita 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AD - Andorra 1
AQ - Antartide 1
AU - Australia 1
BB - Barbados 1
BN - Brunei Darussalam 1
BW - Botswana 1
CR - Costa Rica 1
EG - Egitto 1
KR - Corea 1
LK - Sri Lanka 1
Totale 15.198
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Città #
Dublin 1.042
Moscow 981
Singapore 678
Dallas 599
Jacksonville 596
Ashburn 592
Chandler 554
Nyköping 527
Hong Kong 434
Beijing 381
Princeton 163
Messina 145
Los Angeles 144
Medford 136
Cambridge 126
Dearborn 121
The Dalles 117
Des Moines 107
São Paulo 78
Boardman 76
Ann Arbor 73
Buffalo 73
Dong Ket 72
New York 72
Warsaw 68
Ho Chi Minh City 57
Munich 48
Redondo Beach 47
Rio de Janeiro 42
Lancaster 38
Jinan 36
Belo Horizonte 32
Tianjin 32
Hanoi 31
Woodbridge 31
Wilmington 30
Seattle 27
Johannesburg 24
Curitiba 23
San Mateo 23
Shenyang 23
Brno 22
Santa Clara 22
Stockholm 22
Pune 21
Rome 21
Tashkent 21
Brasília 20
Brooklyn 20
Brussels 20
Milan 20
Montreal 20
Houston 19
Nanjing 19
Chicago 18
Guarulhos 18
Denver 17
London 17
Porto Alegre 17
Manaus 16
Tokyo 16
Campinas 15
Hyderabad 15
Helsinki 14
Salvador 14
San Francisco 14
Atlanta 13
Norwalk 13
Poplar 13
Boston 12
Chennai 12
Augusta 11
Nuremberg 11
Orem 11
Amsterdam 10
Ankara 10
Baku 10
Cape Town 10
Da Nang 10
Guayaquil 10
Hebei 10
Nanchang 10
Zhengzhou 10
Baghdad 9
Biên Hòa 9
Frankfurt am Main 9
Hangzhou 9
Jakarta 9
Mumbai 9
Olomouc 9
Taizhou 9
Vienna 9
Clearwater 8
Haikou 8
Joinville 8
Mexico City 8
Ningbo 8
Phoenix 8
Quito 8
Asunción 7
Totale 9.287
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Nome #
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 218
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 161
"Click" on PLGA-PEG and hyaluronic acid: Gaining access to anti-leishmanial pentamidine bioconjugates 156
A hyaluronic acid–pentamidine bioconjugate as a macrophage mediated drug targeting delivery system for the treatment of leishmaniasis 154
Polimorfismi del gene PON1, attività della paraoxonase sierica ed effetti antiossidanti dell’atorvastatina in soggetti del sud Italia 150
5-Phenyl-9H-1,3-dioxolo[4,5-h][2,3]-benzodiazepin-8(7H)-one 146
Antimicrobial and antiprotozoal activities of silver coordination polymers derived from the asymmetric halogenated Schiff base ligands 146
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 145
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 138
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 135
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis 134
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 132
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 132
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 130
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 130
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 127
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 127
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 126
Antimicrobial peptide capsids of de novo design 125
Antileukemia Activity and Mechanism of Platinum(II)-Based Metal Complexes 124
Silibinin-conjugated graphene nanoplatform: Synthesis, characterization and biological evaluation 123
α,α-Difluoromethyl Ketone Moiety: A Promising Functional Group for Targeting Druggable Enzymes 120
Chloro-substituted Hoveyda-Grubbs ruthenium carbene: investigation of electronic effects 118
Anticancer study of heterobimetallic platinum(II)-ruthenium(II) and platinum(II)-rhodium(III) complexes with bridging dithiooxamide ligand 118
4,5-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 115
Supramolecular assembly of pentamidine and polymeric cyclodextrin bimetallic core–shell nanoarchitectures 114
6,7-Methylenedioxyquinazolin-4-ones as Anticonvulsant Agents 113
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 113
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 113
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 112
Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors 112
Falcipain-2 inhibitors 108
Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE 108
Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Bearing a Pyrazole Scaffold and a Cinnamoyl Linker 108
Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist 107
Synthesis, computational investigation and biological evaluation of α,α-difluoromethyl ketones embodying pyrazole and isoxazole nuclei as COX inhibitors 106
Chloro-substituted Hoveyda-Grubbs ruthenium carbene: Investigation of electronic effects 106
6,7-Methylenedioxyphthalazin-1(2H)-ones as novel and potent anticonvulsant agents 106
PREPARATION OF PLA-BASED NANOPARTICLES LOADED WITH SALINOMYCIN AND FOLIC ACID 106
Peptide-based α,α-Difluoromethyl Ketone as new inhibitor of Pathogenic Coronavirus Mpro 106
Design, synthesis and biological evaluation of peptidomimetics boronic acids targeting 20S proteasome 105
Pseudo-Dipeptide Bearing α,α-Difluoromethyl Ketone Moiety as Electrophilic Warhead with Activity against Coronaviruses 104
Novel potent AMPA/kainate receptor antagonists: Synthesis and anticonvulsant activity of a series of 2-[(4- alkylsemicarbazono)-(4-aminophenyl)methyl]-4,5- methylenedioxyphenylacetic acid alkyl esters 103
SARS-CoV-2 Mpro: A Potential Target for Peptidomimetics and Small-Molecule Inhibitors 103
Reazioni di cross metathesis: applicazione alla sintesi di peptidomimetici potenziali inibitori di falcipaina-2 101
STRATEGIES FOR SYNTHESIS OF CONFORMATIONALLY CONSTRAINED GLUTAMATE ANALOGUES 101
Hydrogels for the Delivery of Plant-Derived (Poly)Phenols 100
Fluorine-based pseudopeptides from halocarbene transfer reaction: synthesis and biological perspectives 100
Synthesis of C3/C1-Substituted Tetrahydroisoquinolines 100
DEVELOPMENT OF NOVEL PEPTIDOMIMETICS CONTAINIG A VINYL SULFONE MOIETY AS PROTEASOME INHIBITORS 99
Development of peptidomimetic boronates as proteasome inhibitors 99
Synthesis and anticonvulsant activity of novel and potent 6,7- methylenedioxyphthalazin-1(2H)-ones 98
Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: The Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives 98
N-Hydroxypyrazolyl Glycine Derivatives as Selective N-Methyl-D-aspartic Acid Receptor Ligands 97
Synthesis and anticonvulsant activity of novel and potent 1- aryl-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3- benzodiazepin-4-ones 97
Direct and chemoselective transfer of the difluoromethyl (CHF2) unit into carbon-electrophiles under nucleophilic regime 97
2,3-Benzodiazepine-based noncompetitive AMPAR antagonists: design, synthesis, binding affinity and mechanism of inhibition of the GluR2Qflip homomeric receptor channel 97
Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents 95
Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: identification of the 1-(4-amino,3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent 95
Glutamate Binding-Site Ligands of NMDA Receptors 95
Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF2-Carbene Equivalent 95
Novel Cinnamic Esters as SARS-CoV-2 Mpro Inhibitors with In Vitro Activity against Human Coronaviruses 94
Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain 94
Synthesis and structure-activity relationship of 2,3-benzodiazepines AMPA receptor antagonists 94
Characterization of the binding site in a series of AMPA receptor antagonists. 93
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF PEPTIDOMIMETIC FALCIPAIN-2 INHIBITORS AS ANTIMALARIAL AGENTS 93
Synthesis and anticonvulsant activity of novel and potent 2,3- benzodiazepine AMPA/kainate receptor antagonists 92
Cap.21. Antitrombotici 92
Synthesis, Characterization and Biological Profile of Pentamidine-based Nano-antimicrobials 91
Synthesis and Molecular Modeling Studies of Derivatives of a Highly Potent Peptidomimetic Vinyl Ester as Falcipain-2 Inhibitors 91
Subunit-specific agonist activity at NR2A, NR2B, NR2C, and NR2D containing N-methyl-D-aspartate glutamate receptors. 90
Novel peptidomimetics as antiplasmodial falcipain-2 inhibitors 90
Development of peptidomimetic boronates as proteasome inhibitors 90
Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents 90
Cross-metathesis reactions applications to the synthesis of peptidomimetics as potent falcipain-2 inhibitors 90
Anticancer activity and morphological analysis of Pt(II) complexes: Their DFT approach, docking simulation, and ADME-Tox profiling 88
Synthesis, chiral resolution and enantiopharmacology of a potent 2,3-benzodiazepine as noncompetitive AMPA receptor antagonist 88
Nuovi derivati dell’acido 4,5-metilendiossi-fenilacetico antagonisti del recettore AMPA/KA. 88
Copper(II) complexes with tridentate halogen‐substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving group and ligand flexibility on antiproliferative activities 88
Novel Class of Proteasome Inhibitors: In Silico and In Vitro Evaluation of Diverse Chloro(trifluoromethyl)aziridines 87
Structure-activity relationships of 2,3-benzodiazepines as AMPA/KA receptor antagonists 87
Synthesis and biological evaluation of new 2-amino-6-(trifluoromethoxy)benzoxazole derivatives, analogues of riluzole. 87
Development of Peptidomimetics with a Vinyl Sulfone Warhead as Irreversible Falcipain-2 Inhibitors 86
Nonpeptidic Vinyl and Allyl Phosphonates as Falcipain-2 Inhibitors 86
Synthesis and anti-HIV activity evaluation of new phenyl ethyl thiourea (PET) derivatives 86
Development of nonpeptidic vinyl and allyl phosphonates as active-site-directed inhibitors of falcipain-2 85
Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors 85
Silibinin conjugated graphene and hyaluronic acid platforms for osteosarcoma targeting 85
Synthesis and anticonvulsant activity of new 2,3-benzodiazepines as AMPA receptor antagonists 84
Novel peptidomimetic cysteine protease inhibitors as potential antimalarial agents 84
Synthesis of constrained dipeptide mimics containing the benzodiazepine scaffold 84
Antibacterial, antioxidant and anti-inflammatory properties of essential oils in combination 83
Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors 83
Synthesis of Peptidomimetics with the Benzodiazepine Nucleus as beta-turn mimic 83
Characterization of the mechanism of anticonvulsant activity for a selected set of putative AMPA receptor antagonists 82
Synthesis and antitumor activity of 1,3-benzodioxole derivatives 82
Synthesis and in vitro antitumour activity evaluation of 1-aryl-1H,3H-thiazolo[4,3-b]-quinazolines 82
Progettazione e sintesi di nuovi antagonisti noncompetitivi del recettore AMPA 82
Synthesis of Nanoterapeutics based on G/HA platforms for osteosarcoma targeting. 82
Synthesis of 5-substituted 7,9-dihydro-8H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-8-ones as anticonvulsant agents 81
Totale 10.549
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Categoria #
all - tutte 56.318
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 56.318
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021551 0 0 0 0 0 99 16 83 24 162 57 110
2021/2022978 13 169 15 30 19 4 70 40 7 33 249 329
2022/20232.640 208 196 109 185 172 271 43 120 1.237 12 62 25
2023/2024598 42 84 59 147 64 75 5 31 6 20 10 55
2024/20253.290 55 45 105 162 165 60 110 709 848 197 258 576
2025/20265.263 417 738 690 658 764 1.996 0 0 0 0 0 0
Totale 15.579