IRIS
MICALE, Nicola
 Distribuzione geografica
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Continente #
EU - Europa 7.737
NA - Nord America 7.509
AS - Asia 4.167
SA - Sud America 1.481
Continente sconosciuto - Info sul continente non disponibili 396
AF - Africa 145
OC - Oceania 6
AN - Antartide 1
Totale 21.442
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Nazione #
US - Stati Uniti d'America 7.263
RU - Federazione Russa 3.865
SG - Singapore 1.753
BR - Brasile 1.284
CN - Cina 1.082
IE - Irlanda 1.045
SE - Svezia 802
IT - Italia 602
HK - Hong Kong 458
UA - Ucraina 314
VN - Vietnam 299
DE - Germania 296
FR - Francia 198
GB - Regno Unito 197
FI - Finlandia 150
IN - India 140
CA - Canada 115
PL - Polonia 75
AR - Argentina 74
BD - Bangladesh 73
ZA - Sudafrica 50
TR - Turchia 47
IQ - Iraq 44
MX - Messico 39
ID - Indonesia 37
ES - Italia 35
JP - Giappone 35
CZ - Repubblica Ceca 33
EC - Ecuador 31
UZ - Uzbekistan 27
MA - Marocco 25
CO - Colombia 24
NL - Olanda 24
BE - Belgio 22
PK - Pakistan 19
SA - Arabia Saudita 18
TN - Tunisia 16
VE - Venezuela 16
AE - Emirati Arabi Uniti 15
IL - Israele 15
PE - Perù 15
AT - Austria 14
PY - Paraguay 14
CR - Costa Rica 13
DZ - Algeria 12
HN - Honduras 12
PH - Filippine 12
JM - Giamaica 11
TT - Trinidad e Tobago 11
AZ - Azerbaigian 10
CW - ???statistics.table.value.countryCode.CW??? 10
MY - Malesia 10
OM - Oman 10
CL - Cile 9
LT - Lituania 9
NI - Nicaragua 8
NP - Nepal 8
UY - Uruguay 8
DK - Danimarca 7
EU - Europa 7
KE - Kenya 7
SV - El Salvador 7
AL - Albania 6
BO - Bolivia 6
DO - Repubblica Dominicana 6
GE - Georgia 6
GT - Guatemala 6
LB - Libano 6
SC - Seychelles 6
CI - Costa d'Avorio 5
ET - Etiopia 5
IR - Iran 5
BH - Bahrain 4
BY - Bielorussia 4
GP - Guadalupe 4
HU - Ungheria 4
KZ - Kazakistan 4
LV - Lettonia 4
PA - Panama 4
PT - Portogallo 4
QA - Qatar 4
RS - Serbia 4
SK - Slovacchia (Repubblica Slovacca) 4
SN - Senegal 4
TW - Taiwan 4
AM - Armenia 3
BG - Bulgaria 3
CH - Svizzera 3
EE - Estonia 3
GR - Grecia 3
JO - Giordania 3
KR - Corea 3
PR - Porto Rico 3
TH - Thailandia 3
AO - Angola 2
AU - Australia 2
BB - Barbados 2
GA - Gabon 2
HT - Haiti 2
KG - Kirghizistan 2
Totale 21.029
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Città #
Moscow 1.181
Dublin 1.044
Ashburn 1.035
Singapore 940
Dallas 610
Jacksonville 600
Chandler 554
Nyköping 527
Hong Kong 455
San Jose 425
Beijing 396
Council Bluffs 308
The Dalles 208
Messina 164
Princeton 163
Los Angeles 160
Medford 136
Lauterbourg 135
Cambridge 126
Dearborn 121
Des Moines 109
New York 92
São Paulo 84
Boardman 81
Buffalo 75
Ann Arbor 73
Dong Ket 72
Warsaw 71
Ho Chi Minh City 70
Santa Clara 59
Tianjin 58
Hanoi 50
Munich 48
Redondo Beach 47
Rome 47
Rio de Janeiro 44
Lancaster 39
Chicago 38
Jinan 36
Guangzhou 34
Frankfurt am Main 33
Houston 33
Orem 33
Belo Horizonte 32
Milan 32
Woodbridge 31
Seattle 30
Wilmington 30
Columbus 29
Montreal 29
Tokyo 29
Brooklyn 27
Tashkent 27
Johannesburg 25
Chennai 23
Curitiba 23
Phoenix 23
San Mateo 23
Shanghai 23
Shenyang 23
Stockholm 23
Atlanta 22
Brno 22
Pune 22
Brasília 21
Denver 21
Brussels 20
London 20
Shenzhen 20
Nanjing 19
Porto Alegre 19
San Francisco 19
Guarulhos 18
North Bergen 17
Campinas 16
Manaus 16
Hyderabad 15
Las Vegas 15
Mumbai 15
Nuremberg 15
Amsterdam 14
Baghdad 14
Boston 14
Helsinki 14
Philadelphia 14
Salvador 14
Norwalk 13
Poplar 13
Naples 12
Ankara 11
Augusta 11
Cape Town 11
Da Nang 11
Quito 11
Verona 11
Zhengzhou 11
Baku 10
Guayaquil 10
Hebei 10
Jakarta 10
Totale 11.687
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Nome #
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 272
"Click" on PLGA-PEG and hyaluronic acid: Gaining access to anti-leishmanial pentamidine bioconjugates 221
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 214
Antimicrobial and antiprotozoal activities of silver coordination polymers derived from the asymmetric halogenated Schiff base ligands 211
α,α-Difluoromethyl Ketone Moiety: A Promising Functional Group for Targeting Druggable Enzymes 208
A hyaluronic acid–pentamidine bioconjugate as a macrophage mediated drug targeting delivery system for the treatment of leishmaniasis 207
5-Phenyl-9H-1,3-dioxolo[4,5-h][2,3]-benzodiazepin-8(7H)-one 205
Antileukemia Activity and Mechanism of Platinum(II)-Based Metal Complexes 198
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 190
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis 189
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 188
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 180
Polimorfismi del gene PON1, attività della paraoxonase sierica ed effetti antiossidanti dell’atorvastatina in soggetti del sud Italia 178
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 176
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 174
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 174
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 173
Synthesis, computational investigation and biological evaluation of α,α-difluoromethyl ketones embodying pyrazole and isoxazole nuclei as COX inhibitors 168
Supramolecular assembly of pentamidine and polymeric cyclodextrin bimetallic core–shell nanoarchitectures 167
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 166
Hydrogels for the Delivery of Plant-Derived (Poly)Phenols 166
Anticancer study of heterobimetallic platinum(II)-ruthenium(II) and platinum(II)-rhodium(III) complexes with bridging dithiooxamide ligand 166
Chloro-substituted Hoveyda-Grubbs ruthenium carbene: Investigation of electronic effects 163
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 162
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 162
Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Bearing a Pyrazole Scaffold and a Cinnamoyl Linker 162
Chloro-substituted Hoveyda-Grubbs ruthenium carbene: investigation of electronic effects 157
Anticancer activity and morphological analysis of Pt(II) complexes: Their DFT approach, docking simulation, and ADME-Tox profiling 156
4,5-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 156
6,7-Methylenedioxyquinazolin-4-ones as Anticonvulsant Agents 156
Falcipain-2 inhibitors 156
6,7-Methylenedioxyphthalazin-1(2H)-ones as novel and potent anticonvulsant agents 156
Antimicrobial peptide capsids of de novo design 153
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 151
Silibinin-conjugated graphene nanoplatform: Synthesis, characterization and biological evaluation 151
Peptide-based α,α-Difluoromethyl Ketone as new inhibitor of Pathogenic Coronavirus Mpro 151
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 150
Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist 149
SARS-CoV-2 Mpro: A Potential Target for Peptidomimetics and Small-Molecule Inhibitors 149
Antibacterial, antioxidant and anti-inflammatory properties of essential oils in combination 148
Pseudo-Dipeptide Bearing α,α-Difluoromethyl Ketone Moiety as Electrophilic Warhead with Activity against Coronaviruses 147
PREPARATION OF PLA-BASED NANOPARTICLES LOADED WITH SALINOMYCIN AND FOLIC ACID 144
Novel Class of Proteasome Inhibitors: In Silico and In Vitro Evaluation of Diverse Chloro(trifluoromethyl)aziridines 142
Glutamate Binding-Site Ligands of NMDA Receptors 141
Cap.21. Antitrombotici 141
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 139
2,3-Benzodiazepine-based noncompetitive AMPAR antagonists: design, synthesis, binding affinity and mechanism of inhibition of the GluR2Qflip homomeric receptor channel 139
Cross-metathesis reactions applications to the synthesis of peptidomimetics as potent falcipain-2 inhibitors 137
Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE 137
Novel Cinnamic Esters as SARS-CoV-2 Mpro Inhibitors with In Vitro Activity against Human Coronaviruses 136
Synthesis of C3/C1-Substituted Tetrahydroisoquinolines 136
Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF2-Carbene Equivalent 134
Design, synthesis and biological evaluation of peptidomimetics boronic acids targeting 20S proteasome 133
Fluorine-based pseudopeptides from halocarbene transfer reaction: synthesis and biological perspectives 133
Novel potent AMPA/kainate receptor antagonists: Synthesis and anticonvulsant activity of a series of 2-[(4- alkylsemicarbazono)-(4-aminophenyl)methyl]-4,5- methylenedioxyphenylacetic acid alkyl esters 132
Direct and chemoselective transfer of the difluoromethyl (CHF2) unit into carbon-electrophiles under nucleophilic regime 132
Synthesis, Characterization and Biological Profile of Pentamidine-based Nano-antimicrobials 130
STRATEGIES FOR SYNTHESIS OF CONFORMATIONALLY CONSTRAINED GLUTAMATE ANALOGUES 130
Development of peptidomimetic boronates as proteasome inhibitors 130
Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents 130
Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: The Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives 129
Copper(II) complexes with tridentate halogen‐substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving group and ligand flexibility on antiproliferative activities 129
Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors 128
Development of peptidomimetic boronates as proteasome inhibitors 128
DEVELOPMENT OF NOVEL PEPTIDOMIMETICS CONTAINIG A VINYL SULFONE MOIETY AS PROTEASOME INHIBITORS 127
Synthesis of α-fluorocinnamate derivatives as novel cathepsin S inhibitors with in vitro antiproliferative activity against pancreatic cancer cells 126
Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors 124
Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain 124
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF PEPTIDOMIMETIC FALCIPAIN-2 INHIBITORS AS ANTIMALARIAL AGENTS 124
Synthesis and anticonvulsant activity of novel and potent 6,7- methylenedioxyphthalazin-1(2H)-ones 123
Natural product-based hybrids as potential candidates for the treatment of cancer: Focus on curcumin and resveratrol 123
Synthesis and anticonvulsant activity of novel and potent 1- aryl-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3- benzodiazepin-4-ones 121
Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: identification of the 1-(4-amino,3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent 121
Novel peptidomimetics as antiplasmodial falcipain-2 inhibitors 121
Synthesis and Molecular Modeling Studies of Derivatives of a Highly Potent Peptidomimetic Vinyl Ester as Falcipain-2 Inhibitors 121
Biological evaluation, DFT, MEP, HOMO-LUMO analysis and ensemble docking studies of Zn(II) complexes of bidentate and tetradentate Schiff base ligands as antileukemia agents 121
Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors 119
Direct and chemoselective synthesis α,α-difluoromethylketones under transfer of (CHF2) unit 118
N-Hydroxypyrazolyl Glycine Derivatives as Selective N-Methyl-D-aspartic Acid Receptor Ligands 117
Reazioni di cross metathesis: applicazione alla sintesi di peptidomimetici potenziali inibitori di falcipaina-2 117
Subunit-specific agonist activity at NR2A, NR2B, NR2C, and NR2D containing N-methyl-D-aspartate glutamate receptors. 117
Synthesis and biological evaluation of new 2-amino-6-(trifluoromethoxy)benzoxazole derivatives, analogues of riluzole. 117
Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents 116
Synthesis of 5-substituted 7,9-dihydro-8H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-8-ones as anticonvulsant agents 116
Nonpeptidic Vinyl and Allyl Phosphonates as Falcipain-2 Inhibitors 116
Synthesis and structure-activity relationship of 2,3-benzodiazepines AMPA receptor antagonists 115
Synthesis, solution behaviour and potential anticancer activity of new trinuclear organometallic palladium(II) complex of S-1-phenylethyl dithiooxamide: Comparison with the trinuclear heterobimetallic platinum(II) analogue 115
Synthesis of benzothiazole derivatives and their biological evaluation as anticancer agents 114
Synthesis, chiral resolution and enantiopharmacology of a potent 2,3-benzodiazepine as noncompetitive AMPA receptor antagonist 113
Development of nonpeptidic vinyl and allyl phosphonates as active-site-directed inhibitors of falcipain-2 113
Peptidyl fluoromethyl ketones and their applications in medicinal chemistry 113
Silibinin conjugated graphene and hyaluronic acid platforms for osteosarcoma targeting 112
Novel peptidomimetic cysteine protease inhibitors as potential antimalarial agents 111
Physicochemical properties of inclusion complexes of highly soluble β-cyclodextrins with highly hydrophobic testosterone propionate 111
Characterization of the binding site in a series of AMPA receptor antagonists. 110
Development of Peptidomimetics with a Vinyl Sulfone Warhead as Irreversible Falcipain-2 Inhibitors 109
Nuovi derivati dell’acido 4,5-metilendiossi-fenilacetico antagonisti del recettore AMPA/KA. 109
Cytotoxic oxidovanadium(IV) complexes of tridentate halogen-substituted Schiff bases: First dinuclear V(IV) complexes with O → VIV = O → VIV = O core 109
Synthesis and in vitro antitumour activity evaluation of 1-aryl-1H,3H-thiazolo[4,3-b]-quinazolines 108
SYNTHESIS OF PYRAZOLE DERIVATIVES DESIGNED AS POTENTIAL INHIBITORS OF DIFFERENT HDAC ISOFORMS 108
Totale 14.415
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Categoria #
all - tutte 74.301
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 74.301
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022751 0 0 0 0 19 4 70 40 7 33 249 329
2022/20232.640 208 196 109 185 172 271 43 120 1.237 12 62 25
2023/2024598 42 84 59 147 64 75 5 31 6 20 10 55
2024/20253.290 55 45 105 162 165 60 110 709 848 197 258 576
2025/20269.352 417 738 690 658 764 2.073 1.102 1.123 1.075 360 184 168
2026/20271.774 168 353 480 664 109 0 0 0 0 0 0 0
Totale 21.442