MICALE, Nicola
 Distribuzione geografica
Continente #
NA - Nord America 3.244
EU - Europa 3.087
AS - Asia 1.041
SA - Sud America 25
Continente sconosciuto - Info sul continente non disponibili 8
AF - Africa 6
OC - Oceania 3
Totale 7.414
Nazione #
US - Stati Uniti d'America 3.227
IE - Irlanda 1.040
SE - Svezia 778
SG - Singapore 448
CN - Cina 437
IT - Italia 370
UA - Ucraina 295
DE - Germania 209
FI - Finlandia 139
GB - Regno Unito 105
VN - Vietnam 74
IN - India 54
PL - Polonia 36
CZ - Repubblica Ceca 31
RU - Federazione Russa 23
BE - Belgio 21
BR - Brasile 18
CA - Canada 13
AT - Austria 10
ID - Indonesia 9
EU - Europa 7
NL - Olanda 6
ES - Italia 4
FR - Francia 4
IR - Iran 4
CL - Cile 3
JP - Giappone 3
LV - Lettonia 3
ZA - Sudafrica 3
BY - Bielorussia 2
HK - Hong Kong 2
HU - Ungheria 2
IL - Israele 2
LT - Lituania 2
MX - Messico 2
NZ - Nuova Zelanda 2
PA - Panama 2
PK - Pakistan 2
PT - Portogallo 2
UY - Uruguay 2
UZ - Uzbekistan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AU - Australia 1
BD - Bangladesh 1
BG - Bulgaria 1
BO - Bolivia 1
CH - Svizzera 1
CI - Costa d'Avorio 1
DK - Danimarca 1
EC - Ecuador 1
EE - Estonia 1
IQ - Iraq 1
MA - Marocco 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TN - Tunisia 1
TR - Turchia 1
Totale 7.414
Città #
Dublin 1.039
Jacksonville 596
Chandler 554
Nyköping 527
Singapore 361
Beijing 215
Ashburn 200
Princeton 163
Messina 137
Medford 136
Cambridge 126
Dearborn 121
Des Moines 107
Boardman 76
Ann Arbor 73
Dong Ket 72
Lancaster 38
Warsaw 36
Jinan 35
Woodbridge 31
Wilmington 30
Los Angeles 29
San Mateo 23
Shenyang 23
Brno 22
Pune 21
Rome 21
Brussels 20
Nanjing 19
Munich 18
Seattle 17
Milan 16
Hyderabad 15
Norwalk 13
Tianjin 13
Helsinki 12
New York 12
Hebei 10
Nanchang 10
Zhengzhou 10
Augusta 9
Taizhou 9
Clearwater 8
Haikou 8
Hangzhou 8
Houston 8
Ningbo 8
Olomouc 8
Santa Clara 8
Vienna 8
Francofonte 7
Ottawa 7
Jakarta 6
Mumbai 6
Auburn Hills 5
Bologna 5
Bonn 5
Fuzhou 5
Jiaxing 5
Padova 5
Clifton 4
London 4
Nuremberg 4
Reggio Calabria 4
Saint Petersburg 4
Shanghai 4
Siracusa 4
Taiyuan 4
Cape Town 3
Changsha 3
Chicago 3
Guangzhou 3
Hefei 3
Kunming 3
Lanzhou 3
Las Vegas 3
Leawood 3
Madrid 3
Richmond 3
Sevastopol 3
Tappahannock 3
Washington 3
Amsterdam 2
Ardabil 2
Auckland 2
Bandung 2
Borghetto Santo Spirito 2
Boston 2
Camisano Vicentino 2
Carlsbad 2
Catania 2
Cavallino 2
Cosenza 2
Dongguan 2
Espoo 2
Fiorenzuola D'arda 2
Frattamaggiore 2
Groningen 2
Kemerovo 2
Luis Eduardo Magalhães 2
Totale 5.245
Nome #
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 136
Polimorfismi del gene PON1, attività della paraoxonase sierica ed effetti antiossidanti dell’atorvastatina in soggetti del sud Italia 104
Antimicrobial peptide capsids of de novo design 87
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 83
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 78
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 73
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 73
A hyaluronic acid–pentamidine bioconjugate as a macrophage mediated drug targeting delivery system for the treatment of leishmaniasis 73
Silibinin-conjugated graphene nanoplatform: Synthesis, characterization and biological evaluation 73
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 72
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 71
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 70
Antimicrobial and antiprotozoal activities of silver coordination polymers derived from the asymmetric halogenated Schiff base ligands 70
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 69
5-Phenyl-9H-1,3-dioxolo[4,5-h][2,3]-benzodiazepin-8(7H)-one 67
"Click" on PLGA-PEG and hyaluronic acid: Gaining access to anti-leishmanial pentamidine bioconjugates 67
N-Hydroxypyrazolyl Glycine Derivatives as Selective N-Methyl-D-aspartic Acid Receptor Ligands 65
Novel potent AMPA/kainate receptor antagonists: Synthesis and anticonvulsant activity of a series of 2-[(4- alkylsemicarbazono)-(4-aminophenyl)methyl]-4,5- methylenedioxyphenylacetic acid alkyl esters 65
Design, synthesis and biological evaluation of peptidomimetics boronic acids targeting 20S proteasome 65
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 64
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 63
STRATEGIES FOR SYNTHESIS OF CONFORMATIONALLY CONSTRAINED GLUTAMATE ANALOGUES 63
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 63
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 63
Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors 63
Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE 63
Synthesis and anticonvulsant activity of novel and potent 6,7- methylenedioxyphthalazin-1(2H)-ones 62
Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents 61
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 61
Synthesis and anticonvulsant activity of novel and potent 1- aryl-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3- benzodiazepin-4-ones 60
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 60
4,5-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 60
Chloro-substituted Hoveyda-Grubbs ruthenium carbene: investigation of electronic effects 59
Synthesis and anticonvulsant activity of novel and potent 2,3- benzodiazepine AMPA/kainate receptor antagonists 58
Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist 58
Falcipain-2 inhibitors 58
DEVELOPMENT OF NOVEL PEPTIDOMIMETICS CONTAINIG A VINYL SULFONE MOIETY AS PROTEASOME INHIBITORS 58
Development of nonpeptidic vinyl and allyl phosphonates as active-site-directed inhibitors of falcipain-2 57
Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: The Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives 57
Synthesis, chiral resolution and enantiopharmacology of a potent 2,3-benzodiazepine as noncompetitive AMPA receptor antagonist 56
Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: identification of the 1-(4-amino,3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent 56
Subunit-specific agonist activity at NR2A, NR2B, NR2C, and NR2D containing N-methyl-D-aspartate glutamate receptors. 56
Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain 56
PREPARATION OF PLA-BASED NANOPARTICLES LOADED WITH SALINOMYCIN AND FOLIC ACID 56
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis 56
Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Bearing a Pyrazole Scaffold and a Cinnamoyl Linker 56
Chloro-substituted Hoveyda-Grubbs ruthenium carbene: Investigation of electronic effects 55
Fluorine-based pseudopeptides from halocarbene transfer reaction: synthesis and biological perspectives 55
Synthesis of C3/C1-Substituted Tetrahydroisoquinolines 55
Development of Peptidomimetics with a Vinyl Sulfone Warhead as Irreversible Falcipain-2 Inhibitors 54
Characterization of the binding site in a series of AMPA receptor antagonists. 54
Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors 54
Synthesis of 5-substituted 7,9-dihydro-8H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-8-ones as anticonvulsant agents 53
Progettazione e sintesi di nuovi antagonisti noncompetitivi del recettore AMPA 53
Copper(II) complexes with tridentate halogen‐substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving group and ligand flexibility on antiproliferative activities 53
Structure-activity relationships of 2,3-benzodiazepines as AMPA/KA receptor antagonists 52
Synthesis and in vitro antitumour activity evaluation of 1-aryl-1H,3H-thiazolo[4,3-b]-quinazolines 52
Novel peptidomimetic cysteine protease inhibitors as potential antimalarial agents 52
Synthesis of Nanoterapeutics based on G/HA platforms for osteosarcoma targeting. 52
Hydrogels for the Delivery of Plant-Derived (Poly)Phenols 52
Characterization of the mechanism of anticonvulsant activity for a selected set of putative AMPA receptor antagonists 51
Peptide-based α,α-Difluoromethyl Ketone as new inhibitor of Pathogenic Coronavirus Mpro 51
Synthesis and anticonvulsant activity of new 2,3-benzodiazepines as AMPA receptor antagonists 50
New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists 50
Structure-activity relationships of 2,3-benzodiazepines as AMPA/KA receptor antagonists. 50
Synthesis and anti-HIV activity evaluation of new phenyl ethyl thiourea (PET) derivatives 50
Glutamate Binding-Site Ligands of NMDA Receptors 50
6,7-Methylenedioxyphthalazin-1(2H)-ones as novel and potent anticonvulsant agents 50
Synthesis and structure-activity relationship of 2,3-benzodiazepines AMPA receptor antagonists 50
SARS-CoV-2 Mpro: A Potential Target for Peptidomimetics and Small-Molecule Inhibitors 50
Synthesis of Peptidomimetics with the Benzodiazepine Nucleus as beta-turn mimic 49
6,7-Methylenedioxyquinazolin-4-ones as Anticonvulsant Agents 49
Novel peptidomimetics as antiplasmodial falcipain-2 inhibitors 49
Synthesis of benzothiazole derivatives and their biological evaluation as anticancer agents 49
Anticancer study of heterobimetallic platinum(II)-ruthenium(II) and platinum(II)-rhodium(III) complexes with bridging dithiooxamide ligand 49
Synthesis and antitumor activity of 1,3-benzodioxole derivatives 48
Synthesis and cytotoxic activity of 1,3-benzodioxole derivatives. Note II 48
Reazioni di cross metathesis: applicazione alla sintesi di peptidomimetici potenziali inibitori di falcipaina-2 48
Development of peptidomimetic boronates as proteasome inhibitors 48
Novel 2H-Isoquinolin-3-ones Falcipain-2 Inhibitors as Antimalarial Agents 47
Nuovi derivati dell’acido 4,5-metilendiossi-fenilacetico antagonisti del recettore AMPA/KA. 47
Novel peptidomimetic cysteine protease inhibitors as antimalarial agents 46
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF PEPTIDOMIMETIC FALCIPAIN-2 INHIBITORS AS ANTIMALARIAL AGENTS 46
Synthesis of Peptidomimetics with the Benzodiazepine Nucleus as beta-turn mimic 46
Design of 1-substituted 2-arylmethyl-4,5-methylenedioxybenzene derivatives as antiseizure agents 45
New 2,3-benzodiazepines as noncompetitive AMPA receptor antagonists. 45
Enantioseparazione, determinazione della configurazione assoluta ed attività anticonvulsivante dell’1-(4-aminofenil)-1,2,3,5-tetraidro-7,8-metilendiossi-4H-2,3-benzodiazepin-4-one. 45
Direct and chemoselective transfer of the difluoromethyl (CHF2) unit into carbon-electrophiles under nucleophilic regime 45
Antiproliferative properties of a few auranofin-related gold(I) and silver(I) complexes in leukemia cells and their interferences with the ubiquitin proteasome system 45
Pseudo-Dipeptide Bearing α,α-Difluoromethyl Ketone Moiety as Electrophilic Warhead with Activity against Coronaviruses 45
Targeting of the Leishmania Mexicana cysteine protease CPB2.8 ΔCTE by decorated fused benzo[b] thiophene scaffold. 44
Synthesis and anticonvulsant activity of new 2,3- benzodiazepines as AMPA receptor antagonists 43
Design and synthesis of a potent and selective peptidomimetic inhibitor of caspase-3 42
Progettazione e sintesi di nuovi antagonisti noncompetivi del recettore AMPA 42
Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents 42
Silibinin conjugated graphene and hyaluronic acid platforms for osteosarcoma targeting 42
Novel Peptidomimetics Containing a Vinyl Ester Moiety as Highly Potent and Selective Falcipain-2 Inhibitors 41
Mechanism of Inhibition of GluA2 AMPA Receptor Channel Opening by 2,3-Benzodiazepine Derivatives: Functional Consequences of Replacing a 7,8-Methylenedioxy with a 7,8-Ethylenedioxy Moiety 41
Synthesis and biological evaluation of new 2-amino-6-(trifluoromethoxy)benzoxazole derivatives, analogues of riluzole. 41
Synthesis and Molecular Modeling Studies of Derivatives of a Highly Potent Peptidomimetic Vinyl Ester as Falcipain-2 Inhibitors 41
Totale 5.670
Categoria #
all - tutte 36.287
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.287


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020432 0 0 0 0 0 0 0 98 9 148 167 10
2020/2021953 102 11 168 55 66 99 16 83 24 162 57 110
2021/2022978 13 169 15 30 19 4 70 40 7 33 249 329
2022/20232.640 208 196 109 185 172 271 43 120 1.237 12 62 25
2023/2024598 42 84 59 147 64 75 5 31 6 20 10 55
2024/2025750 55 45 105 162 165 60 110 48 0 0 0 0
Totale 7.776