IRIS
MICALE, Nicola
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 7.556
NA - Nord America 6.422
AS - Asia 4.147
SA - Sud America 1.477
Continente sconosciuto - Info sul continente non disponibili 383
AF - Africa 136
OC - Oceania 6
AN - Antartide 1
Totale 20.128
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 6.251
RU - Federazione Russa 3.845
SG - Singapore 1.752
BR - Brasile 1.282
CN - Cina 1.080
IE - Irlanda 1.045
SE - Svezia 801
IT - Italia 473
HK - Hong Kong 458
UA - Ucraina 314
VN - Vietnam 299
DE - Germania 293
FR - Francia 193
GB - Regno Unito 181
FI - Finlandia 150
IN - India 140
CA - Canada 76
PL - Polonia 75
AR - Argentina 73
BD - Bangladesh 70
ZA - Sudafrica 50
TR - Turchia 47
IQ - Iraq 44
MX - Messico 39
ID - Indonesia 36
ES - Italia 35
JP - Giappone 35
CZ - Repubblica Ceca 33
EC - Ecuador 31
UZ - Uzbekistan 26
MA - Marocco 25
CO - Colombia 23
NL - Olanda 23
BE - Belgio 22
PK - Pakistan 18
SA - Arabia Saudita 18
TN - Tunisia 16
VE - Venezuela 16
AE - Emirati Arabi Uniti 15
PE - Perù 15
AT - Austria 14
PY - Paraguay 14
PH - Filippine 12
HN - Honduras 11
AZ - Azerbaigian 10
OM - Oman 10
CL - Cile 9
DZ - Algeria 9
JM - Giamaica 9
MY - Malesia 9
CR - Costa Rica 8
NP - Nepal 8
UY - Uruguay 8
EU - Europa 7
KE - Kenya 7
LT - Lituania 7
AL - Albania 6
BO - Bolivia 6
GE - Georgia 6
IL - Israele 6
LB - Libano 6
CI - Costa d'Avorio 5
DO - Repubblica Dominicana 5
ET - Etiopia 5
IR - Iran 5
TT - Trinidad e Tobago 5
BH - Bahrain 4
BY - Bielorussia 4
DK - Danimarca 4
HU - Ungheria 4
LV - Lettonia 4
PA - Panama 4
PT - Portogallo 4
QA - Qatar 4
RS - Serbia 4
SK - Slovacchia (Repubblica Slovacca) 4
SN - Senegal 4
TW - Taiwan 4
AM - Armenia 3
BG - Bulgaria 3
CH - Svizzera 3
GR - Grecia 3
GT - Guatemala 3
JO - Giordania 3
KR - Corea 3
KZ - Kazakistan 3
NI - Nicaragua 3
TH - Thailandia 3
AO - Angola 2
AU - Australia 2
BB - Barbados 2
EE - Estonia 2
GA - Gabon 2
KG - Kirghizistan 2
LA - Repubblica Popolare Democratica del Laos 2
LY - Libia 2
MD - Moldavia 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
PR - Porto Rico 2
Totale 19.727
Salva come PNG Salva come JPEG
Città #
Moscow 1.181
Dublin 1.044
Singapore 939
Ashburn 847
Dallas 606
Jacksonville 600
Chandler 554
Nyköping 527
Hong Kong 455
Beijing 395
San Jose 277
Council Bluffs 250
The Dalles 192
Messina 163
Princeton 163
Los Angeles 154
Medford 136
Lauterbourg 135
Cambridge 126
Dearborn 121
Des Moines 108
New York 87
São Paulo 84
Boardman 77
Ann Arbor 73
Buffalo 73
Dong Ket 72
Ho Chi Minh City 70
Warsaw 70
Tianjin 58
Hanoi 50
Munich 48
Redondo Beach 47
Rio de Janeiro 44
Santa Clara 42
Lancaster 39
Jinan 36
Guangzhou 34
Belo Horizonte 32
Frankfurt am Main 32
Woodbridge 31
Orem 30
Wilmington 30
Tokyo 29
Chicago 28
Columbus 28
Houston 28
Rome 27
Seattle 27
Montreal 26
Tashkent 26
Johannesburg 25
Milan 24
Brooklyn 23
Chennai 23
Curitiba 23
San Mateo 23
Shanghai 23
Shenyang 23
Brno 22
Pune 22
Stockholm 22
Brasília 20
Brussels 20
Shenzhen 20
Denver 19
London 19
Nanjing 19
Porto Alegre 19
Guarulhos 18
Atlanta 17
San Francisco 17
Campinas 16
Manaus 16
Hyderabad 15
Mumbai 15
Nuremberg 15
Amsterdam 14
Baghdad 14
Helsinki 14
Salvador 14
Boston 13
Norwalk 13
Poplar 13
Phoenix 12
Ankara 11
Augusta 11
Cape Town 11
Da Nang 11
Quito 11
Zhengzhou 11
Baku 10
Guayaquil 10
Hebei 10
Jakarta 10
Joinville 10
Las Vegas 10
Manchester 10
Mexico City 10
Nanchang 10
Totale 11.132
Salva come PNG Salva come JPEG
Nome #
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 261
"Click" on PLGA-PEG and hyaluronic acid: Gaining access to anti-leishmanial pentamidine bioconjugates 211
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 201
Antimicrobial and antiprotozoal activities of silver coordination polymers derived from the asymmetric halogenated Schiff base ligands 201
α,α-Difluoromethyl Ketone Moiety: A Promising Functional Group for Targeting Druggable Enzymes 200
5-Phenyl-9H-1,3-dioxolo[4,5-h][2,3]-benzodiazepin-8(7H)-one 198
A hyaluronic acid–pentamidine bioconjugate as a macrophage mediated drug targeting delivery system for the treatment of leishmaniasis 195
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis 185
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 184
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 179
Antileukemia Activity and Mechanism of Platinum(II)-Based Metal Complexes 178
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 175
Polimorfismi del gene PON1, attività della paraoxonase sierica ed effetti antiossidanti dell’atorvastatina in soggetti del sud Italia 173
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 169
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 169
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 166
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 163
Supramolecular assembly of pentamidine and polymeric cyclodextrin bimetallic core–shell nanoarchitectures 159
Chloro-substituted Hoveyda-Grubbs ruthenium carbene: Investigation of electronic effects 159
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 159
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 158
Anticancer study of heterobimetallic platinum(II)-ruthenium(II) and platinum(II)-rhodium(III) complexes with bridging dithiooxamide ligand 157
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 156
Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Bearing a Pyrazole Scaffold and a Cinnamoyl Linker 156
Synthesis, computational investigation and biological evaluation of α,α-difluoromethyl ketones embodying pyrazole and isoxazole nuclei as COX inhibitors 154
Chloro-substituted Hoveyda-Grubbs ruthenium carbene: investigation of electronic effects 153
6,7-Methylenedioxyquinazolin-4-ones as Anticonvulsant Agents 152
Hydrogels for the Delivery of Plant-Derived (Poly)Phenols 151
4,5-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 150
Falcipain-2 inhibitors 148
6,7-Methylenedioxyphthalazin-1(2H)-ones as novel and potent anticonvulsant agents 147
Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist 146
Antimicrobial peptide capsids of de novo design 146
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 145
Silibinin-conjugated graphene nanoplatform: Synthesis, characterization and biological evaluation 144
SARS-CoV-2 Mpro: A Potential Target for Peptidomimetics and Small-Molecule Inhibitors 143
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 143
Peptide-based α,α-Difluoromethyl Ketone as new inhibitor of Pathogenic Coronavirus Mpro 142
PREPARATION OF PLA-BASED NANOPARTICLES LOADED WITH SALINOMYCIN AND FOLIC ACID 137
Pseudo-Dipeptide Bearing α,α-Difluoromethyl Ketone Moiety as Electrophilic Warhead with Activity against Coronaviruses 137
Anticancer activity and morphological analysis of Pt(II) complexes: Their DFT approach, docking simulation, and ADME-Tox profiling 136
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 136
Novel Cinnamic Esters as SARS-CoV-2 Mpro Inhibitors with In Vitro Activity against Human Coronaviruses 135
Cross-metathesis reactions applications to the synthesis of peptidomimetics as potent falcipain-2 inhibitors 134
Antibacterial, antioxidant and anti-inflammatory properties of essential oils in combination 133
Novel Class of Proteasome Inhibitors: In Silico and In Vitro Evaluation of Diverse Chloro(trifluoromethyl)aziridines 132
Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE 132
Cap.21. Antitrombotici 132
2,3-Benzodiazepine-based noncompetitive AMPAR antagonists: design, synthesis, binding affinity and mechanism of inhibition of the GluR2Qflip homomeric receptor channel 132
Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF2-Carbene Equivalent 129
Synthesis, Characterization and Biological Profile of Pentamidine-based Nano-antimicrobials 127
Design, synthesis and biological evaluation of peptidomimetics boronic acids targeting 20S proteasome 127
Fluorine-based pseudopeptides from halocarbene transfer reaction: synthesis and biological perspectives 127
Novel potent AMPA/kainate receptor antagonists: Synthesis and anticonvulsant activity of a series of 2-[(4- alkylsemicarbazono)-(4-aminophenyl)methyl]-4,5- methylenedioxyphenylacetic acid alkyl esters 125
Development of peptidomimetic boronates as proteasome inhibitors 125
Development of peptidomimetic boronates as proteasome inhibitors 125
Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents 125
STRATEGIES FOR SYNTHESIS OF CONFORMATIONALLY CONSTRAINED GLUTAMATE ANALOGUES 124
Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors 124
Synthesis of C3/C1-Substituted Tetrahydroisoquinolines 124
Copper(II) complexes with tridentate halogen‐substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving group and ligand flexibility on antiproliferative activities 123
Glutamate Binding-Site Ligands of NMDA Receptors 122
Direct and chemoselective transfer of the difluoromethyl (CHF2) unit into carbon-electrophiles under nucleophilic regime 122
Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: The Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives 120
Synthesis of α-fluorocinnamate derivatives as novel cathepsin S inhibitors with in vitro antiproliferative activity against pancreatic cancer cells 119
DEVELOPMENT OF NOVEL PEPTIDOMIMETICS CONTAINIG A VINYL SULFONE MOIETY AS PROTEASOME INHIBITORS 118
Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors 116
Reazioni di cross metathesis: applicazione alla sintesi di peptidomimetici potenziali inibitori di falcipaina-2 115
Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain 115
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF PEPTIDOMIMETIC FALCIPAIN-2 INHIBITORS AS ANTIMALARIAL AGENTS 115
Synthesis and Molecular Modeling Studies of Derivatives of a Highly Potent Peptidomimetic Vinyl Ester as Falcipain-2 Inhibitors 115
Synthesis and anticonvulsant activity of novel and potent 6,7- methylenedioxyphthalazin-1(2H)-ones 114
Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: identification of the 1-(4-amino,3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent 114
Novel peptidomimetics as antiplasmodial falcipain-2 inhibitors 114
Biological evaluation, DFT, MEP, HOMO-LUMO analysis and ensemble docking studies of Zn(II) complexes of bidentate and tetradentate Schiff base ligands as antileukemia agents 114
Synthesis and biological evaluation of new 2-amino-6-(trifluoromethoxy)benzoxazole derivatives, analogues of riluzole. 112
N-Hydroxypyrazolyl Glycine Derivatives as Selective N-Methyl-D-aspartic Acid Receptor Ligands 111
Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents 111
Synthesis and anticonvulsant activity of novel and potent 1- aryl-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3- benzodiazepin-4-ones 111
Subunit-specific agonist activity at NR2A, NR2B, NR2C, and NR2D containing N-methyl-D-aspartate glutamate receptors. 111
Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors 111
Development of nonpeptidic vinyl and allyl phosphonates as active-site-directed inhibitors of falcipain-2 110
Natural product-based hybrids as potential candidates for the treatment of cancer: Focus on curcumin and resveratrol 110
Synthesis, chiral resolution and enantiopharmacology of a potent 2,3-benzodiazepine as noncompetitive AMPA receptor antagonist 108
Nonpeptidic Vinyl and Allyl Phosphonates as Falcipain-2 Inhibitors 108
Silibinin conjugated graphene and hyaluronic acid platforms for osteosarcoma targeting 108
Synthesis and structure-activity relationship of 2,3-benzodiazepines AMPA receptor antagonists 108
Characterization of the binding site in a series of AMPA receptor antagonists. 106
Nuovi derivati dell’acido 4,5-metilendiossi-fenilacetico antagonisti del recettore AMPA/KA. 106
Peptidyl fluoromethyl ketones and their applications in medicinal chemistry 106
Synthesis of 5-substituted 7,9-dihydro-8H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-8-ones as anticonvulsant agents 105
Novel peptidomimetic cysteine protease inhibitors as potential antimalarial agents 105
Synthesis of benzothiazole derivatives and their biological evaluation as anticancer agents 105
SYNTHESIS OF PYRAZOLE DERIVATIVES DESIGNED AS POTENTIAL INHIBITORS OF DIFFERENT HDAC ISOFORMS 105
Direct and chemoselective synthesis α,α-difluoromethylketones under transfer of (CHF2) unit 105
Physicochemical properties of inclusion complexes of highly soluble β-cyclodextrins with highly hydrophobic testosterone propionate 104
Synthesis, solution behaviour and potential anticancer activity of new trinuclear organometallic palladium(II) complex of S-1-phenylethyl dithiooxamide: Comparison with the trinuclear heterobimetallic platinum(II) analogue 104
Synthesis and anticonvulsant activity of new 2,3-benzodiazepines as AMPA receptor antagonists 103
Development of Peptidomimetics with a Vinyl Sulfone Warhead as Irreversible Falcipain-2 Inhibitors 103
Synthesis and anticonvulsant activity of novel and potent 2,3- benzodiazepine AMPA/kainate receptor antagonists 102
Totale 13.668
Salva come PNG Salva come JPEG
Categoria #
all - tutte 69.070
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 69.070
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022965 0 169 15 30 19 4 70 40 7 33 249 329
2022/20232.640 208 196 109 185 172 271 43 120 1.237 12 62 25
2023/2024598 42 84 59 147 64 75 5 31 6 20 10 55
2024/20253.290 55 45 105 162 165 60 110 709 848 197 258 576
2025/20269.352 417 738 690 658 764 2.073 1.102 1.123 1.075 360 184 168
2026/2027460 169 291 0 0 0 0 0 0 0 0 0 0
Totale 20.128