Spiro tetrahydropyridine derivatives 4 and 5 were diastereoselectively prepared in good yield by reacting chalcones 3 with azolin-5-ones 1 and 2. From benzalacetones 10, the reaction occurred only with isoxazolin-5-ones 1 leading to spirans 11
MIRC reactions of (E)-chalcones with azol-5-ones - A diastereoselective entry to novel spiro tetrahydropyridine derivatives
RISITANO, Francesco;GRASSI, Giovanni;FOTI, Francesco;ROMEO, Roberto
2002-01-01
Abstract
Spiro tetrahydropyridine derivatives 4 and 5 were diastereoselectively prepared in good yield by reacting chalcones 3 with azolin-5-ones 1 and 2. From benzalacetones 10, the reaction occurred only with isoxazolin-5-ones 1 leading to spirans 11File in questo prodotto:
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