Comprehensive two-dimensional liquid chromatography (LC×LC) offers much higher peak capacities than single dimension separations. The degree of orthogonality between both dimensions is a critical factor for obtaining higher values for peak capacity. This review illustrates the benefits of LC×LC in food analysis and discusses the combination of LC modes used in the two dimensions, and the nature of the samples analyzed.
Combining orthogonal comprehensive two-dimensional liquid chromatography methods in food analysis
CACCIOLA, FRANCESCO;BECCARIA, MARCO;DONATO, Paola Agata Eustochia;MONDELLO, Luigi;DUGO, Paola
2014-01-01
Abstract
Comprehensive two-dimensional liquid chromatography (LC×LC) offers much higher peak capacities than single dimension separations. The degree of orthogonality between both dimensions is a critical factor for obtaining higher values for peak capacity. This review illustrates the benefits of LC×LC in food analysis and discusses the combination of LC modes used in the two dimensions, and the nature of the samples analyzed.File in questo prodotto:
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