Limonoids are human health promoters, and have many pharmacological properties: anticancer, antioxidant, antibacterial and antifungal. To the best of the authors' knowledge, there are no previous reports on the composition of limonoids in bergamot fruits, so the aim of this work was to characterize bergamot peel, pulp, seed and juice. Samples analysed showed the presence of both limonoids aglycones and glucosides. Limonoid aglycones are the most abundant in seeds and peels (70 and 80% of the total, respectively), while limonoid glucosides are the more abundant in juices and pulps (61 and 76% of the total, respectively). Moreover a method to isolate pure limonoids from bergamot seeds and juice by means of a 2D-HPLC/PDA/MS preparative system is proposed. Pure molecules isolated were used to build calibration curves to quantify limonoids in real samples. Isolation of nutraceuticals from seeds and juices can represent an advantageous way to re-evaluate these by-products.

Bergamot (Citrus bergamia Risso) as a source of nutraceuticals: Limonoids and flavonoids

Russo, Marina;ARIGO', ADRIANA
Secondo
;
CALABRO', Maria;MONDELLO, Luigi
Penultimo
;
DUGO, Paola
Ultimo
2016-01-01

Abstract

Limonoids are human health promoters, and have many pharmacological properties: anticancer, antioxidant, antibacterial and antifungal. To the best of the authors' knowledge, there are no previous reports on the composition of limonoids in bergamot fruits, so the aim of this work was to characterize bergamot peel, pulp, seed and juice. Samples analysed showed the presence of both limonoids aglycones and glucosides. Limonoid aglycones are the most abundant in seeds and peels (70 and 80% of the total, respectively), while limonoid glucosides are the more abundant in juices and pulps (61 and 76% of the total, respectively). Moreover a method to isolate pure limonoids from bergamot seeds and juice by means of a 2D-HPLC/PDA/MS preparative system is proposed. Pure molecules isolated were used to build calibration curves to quantify limonoids in real samples. Isolation of nutraceuticals from seeds and juices can represent an advantageous way to re-evaluate these by-products.
2016
File in questo prodotto:
File Dimensione Formato  
407 paper 03-16.pdf

solo utenti autorizzati

Tipologia: Versione Editoriale (PDF)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 752.01 kB
Formato Adobe PDF
752.01 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/3090968
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 75
  • ???jsp.display-item.citation.isi??? 68
social impact