IRIS
CHIMIRRI, Alba
 Distribuzione geografica
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Continente #
NA - Nord America 20.318
EU - Europa 15.473
AS - Asia 7.798
SA - Sud America 2.720
AF - Africa 233
Continente sconosciuto - Info sul continente non disponibili 196
OC - Oceania 11
Totale 46.749
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Nazione #
US - Stati Uniti d'America 19.968
RU - Federazione Russa 7.827
SG - Singapore 3.313
BR - Brasile 2.352
CN - Cina 2.048
IE - Irlanda 1.819
SE - Svezia 1.570
UA - Ucraina 1.112
VN - Vietnam 837
DE - Germania 801
HK - Hong Kong 734
IT - Italia 537
GB - Regno Unito 515
FR - Francia 437
FI - Finlandia 429
IN - India 240
CA - Canada 165
AR - Argentina 138
BD - Bangladesh 85
MX - Messico 82
PL - Polonia 74
IQ - Iraq 71
TR - Turchia 69
EC - Ecuador 62
CZ - Repubblica Ceca 60
JP - Giappone 54
ZA - Sudafrica 54
AT - Austria 50
MA - Marocco 50
NL - Olanda 45
UZ - Uzbekistan 44
BE - Belgio 43
CO - Colombia 42
ES - Italia 41
CI - Costa d'Avorio 34
ID - Indonesia 32
PK - Pakistan 31
VE - Venezuela 29
IR - Iran 28
CL - Cile 25
PY - Paraguay 22
UY - Uruguay 21
SA - Arabia Saudita 20
JM - Giamaica 19
JO - Giordania 19
EG - Egitto 18
KE - Kenya 18
TN - Tunisia 18
AE - Emirati Arabi Uniti 17
IL - Israele 17
NP - Nepal 17
PE - Perù 17
TT - Trinidad e Tobago 15
CR - Costa Rica 14
KG - Kirghizistan 13
OM - Oman 12
BO - Bolivia 11
HN - Honduras 11
KZ - Kazakistan 11
LV - Lettonia 11
AL - Albania 10
AZ - Azerbaigian 10
DZ - Algeria 10
PH - Filippine 10
CH - Svizzera 9
EE - Estonia 9
KR - Corea 9
LB - Libano 9
DO - Repubblica Dominicana 8
GR - Grecia 7
LT - Lituania 7
MY - Malesia 7
NI - Nicaragua 7
NZ - Nuova Zelanda 7
PA - Panama 7
SV - El Salvador 7
A2 - ???statistics.table.value.countryCode.A2??? 6
AO - Angola 6
BG - Bulgaria 6
GT - Guatemala 6
HU - Ungheria 6
RO - Romania 6
SN - Senegal 6
BY - Bielorussia 5
CY - Cipro 5
KW - Kuwait 5
MD - Moldavia 5
RS - Serbia 5
XK - ???statistics.table.value.countryCode.XK??? 5
AU - Australia 4
ET - Etiopia 4
GE - Georgia 4
LU - Lussemburgo 4
NO - Norvegia 4
PR - Porto Rico 4
PS - Palestinian Territory 4
PT - Portogallo 4
SK - Slovacchia (Repubblica Slovacca) 4
BA - Bosnia-Erzegovina 3
BH - Bahrain 3
Totale 46.515
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Città #
Dallas 5.708
Moscow 2.319
Jacksonville 2.080
Ashburn 1.823
Singapore 1.817
Dublin 1.815
Chandler 1.404
Nyköping 1.010
San Jose 800
Beijing 766
Hong Kong 734
Council Bluffs 669
Dong Ket 505
Los Angeles 380
Cambridge 357
Princeton 357
The Dalles 338
Dearborn 333
Lauterbourg 305
Medford 300
Des Moines 274
Boardman 235
Buffalo 173
Ann Arbor 150
São Paulo 146
Lancaster 131
New York 113
Ho Chi Minh City 111
Woodbridge 111
Columbus 105
Wilmington 99
Guangzhou 87
Tianjin 84
Belo Horizonte 76
Hanoi 75
Jinan 73
Santa Clara 73
Hyderabad 68
San Mateo 68
Orem 66
Nanjing 65
Brooklyn 63
Phoenix 59
Milan 57
Houston 56
Pune 56
Warsaw 56
Munich 53
Frankfurt am Main 52
Messina 52
Rio de Janeiro 51
Chicago 49
Redondo Beach 48
Shenyang 48
Brno 47
Montreal 47
Vienna 44
Tashkent 42
Tokyo 42
Brasília 41
Brussels 39
Haikou 39
Denver 38
Baghdad 37
Seattle 37
Rome 36
Atlanta 35
Abidjan 34
London 34
Turku 34
Amsterdam 33
Shanghai 33
Zhengzhou 33
Hebei 31
Stockholm 31
Johannesburg 30
San Francisco 30
Campinas 29
Curitiba 29
Manchester 29
Catania 27
Ningbo 26
Shenzhen 26
Chennai 25
Washington 25
Nuremberg 24
Goiânia 23
Hangzhou 23
Lappeenranta 23
Ottawa 23
Poplar 23
Quito 23
Guayaquil 22
Porto Alegre 22
Saint Petersburg 22
Augusta 21
Fuzhou 21
Taizhou 21
Toronto 21
Mumbai 20
Totale 28.298
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Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 4.625
1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA receptor antagonists 314
1-Phenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 304
1-Aryl-1H,3H-thiazolo[3,4-a]benzimidazole derivatives 300
1,3-THIAZOLIDIN-4-ONES:POTENT AND HIGHLY SELECTIVE ANTI-HIV-1 AGENTS 291
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 284
1-fluoromethyl-1-methyl-1H,3H-thiazolo-[3,4-a]benzimidazole 279
1-Aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide derivatives: synthesis and biological evaluation 278
1H,3H-Thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 259
3,5-dihydro-4H-2,3-benzodiazepine-4-thiones: A new class of AMPA receptor antagonists 225
2-(2,6-dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors 213
AMPA receptor antagonists: Synthesis and pharmacological evaluation 211
2-Hydroxyisoquinoline-1,3(2H,4H)-diones as inhibitors of HIV-1 integrase and reverse transcriptase RNase H domain: Influence of the alkylation of position 4 210
3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]1,3-oxazolidin-2-one 205
5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice. 204
Anticonvulsant activity of azirino[1,2-d][1,4]benzodiazepines and related 1,4-benzodiazepines in mice 199
3H-AZIRINO[1,2-D][1,4]BENZODIAZEPIN-4 (5H)-ONES - SYNTHESIS AND STEREOCHEMISTRY 199
4-[1-(4-Fluorobenzyl)-4-hydroxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid as a prototype to develop dual inhibitors of HIV-1 integration process. 198
5H-[1,2,4]OXADIAZOLO[5,4-D][1,5]BENZOTHIAZEPINES - SYNTHESIS AND STEREOCHEMISTRY 197
Identification of Potent and Selective Human Carbonic Anhydrase VII (hCA VII) Inhibitors 195
Molecular dynamics studies of the wild-type and double mutant HIV-1 integrase complexed with the 5CITEP inhibitor: Mechanism for inhibition and drug resistance 193
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 192
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 191
3D Pharmacophore model and synthesys of NMDA receptor subunit NR2B antagonists 188
Anti-HIV agents: design and discovery of new potent RT inhibitors 185
Design and synthesis of acetylcholinesterase inhibitors 185
7,11b-dihydro-9,10-dimethoxy-3,11b- diphenyl[1,2,4]oxadiazolo[5,4-a]-[2,3]benzodiazepin-6(5H)-one 184
Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(4 '-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline AMPAR antagonists 179
Azirino[1,2-d][1,4]benzodiazepine derivatives and related 1,4- benzodiazepines as anticonvulsant agents in DBA/2 mice 179
Comparative molecular field analysis (CoMFA) and docking studies of non-nucleoside HIV-1 RT inhibitors (NNIs) 178
A new potential approach to block HIV-1 replication via protein–protein interaction and strand-transfer inhibition 178
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 176
HIV-1 integrase strand-transfer inhibitors: Design, synthesis and molecular modeling investigation 176
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 175
Identification of isoquinoline-sulfonamides as potent and selective carbonic anhydrase inhibitors 173
Microwave-assisted synthesis of benzimidazole and thiazolidinone derivatives as HIV-1 RT inhibitors 172
Antiretroviral strategy using multi-target agents 172
3D Pharmacophore Models for 1,2,3,4-Tetrahydroisoquinoline Derivatives Acting as Anticonvulsant Agents 172
Sintesi ed attività anti-HIV di 1H,3H-tiazolo[3,4-a]benzimidazoli-sostituiti 171
Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor. 170
Anticonvulsant activity and plasma level of 2,3-benzodiazepin- 4-ones (CFMs) in genetically epilepsy-prone rats 168
Combined ligand-based and target-based approach to design NR2B/NMDA receptor antagonists 168
Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as Potent Carbonic Anhydrase Inhibitors: Synthesis, Biological Evaluation, and Enzyme−Ligand X-ray Studies 168
DISCOVERY OF NEW INDOLE DERIVATES AS NEUROPROTECTIVE AGENTS 168
Discovery of potent and selective inhibitors of druggable carbonic anhydrase isoforms 167
2-Acetil-1-(4'-clorofenil)-6,7-dimetossi-1,2,3,4-tetraidroisochinolina (Ps3Ac) Potente AMPA-antagonista: Definizione del Profilo Enantiofarmacobiologico 167
Binding modes of noncompetitive AMPA antagonists: a computational approach 166
Analysis of the full-length integrase-DNA complex by a modified approach for DNA docking 166
Novel Potent Anticonvulsant Agent Containing a Tetrahydroisoquinoline Skeleton. 166
Combined strategies for the discovery of ionotropic glutamate receptor antagonists 166
Inhibitors of the Interactions between HIV-1 IN and the Cofactor LEDGF/p75 165
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 164
Nuovi selettivi inibitori dell'anidrasi carbonica: sintesi, SAR e studi sull'interazione enzima/inibitore 162
Compounds with potential anti-tumor activity VII. Synthesis and anti-tumor activity of 1-aryl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines 161
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT 161
Modificazioni strutturali del gruppo dichetoacido (DKA) di potenti inibitori dell'Integrasi dell'HIV-1 161
From NMDA receptor antagonists to discovery of selective σ2 receptor ligands 161
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 160
Synthesis and structure-active relationship of 1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline anticonvulsants 160
Antiretroviral strategy: design and synthesis of HIV-1 IN-LEDGF/p75 interaction inhibitors 159
Binding mode investigation and SAR studies of HIV-1 integrase inhibitors 158
ANNELATED 1,5-BENZODIAZEPINES .1. 3-MEMBERED, 4-MEMBERED, AND 5-MEMBERED RINGS. 157
Optimization of a LC method for the enantio separation of a non-competitive glutamate receptor antagonist, by experimental design methodology 156
ANNELATED 1,5-BENZODIAZEPINES .2. 6 MEMBERED RINGS 156
Nuovi ligandi del recettore NR2B/NMDA a struttura indolica 156
Small Molecules Targeting Protein–Protein Interactions: A Promising Anti-HIV Strategy 156
Annelated 1,5-benzothiazepines 156
Anticonvulsant activity of tetrahydroisoquinoline derivatives as potential new AMPA receptor antagonists 153
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL’INTEGRASI DELL’HIV-1 152
Design and synthesis of 2,3-diaryl-1,3-thiazolidin-4one potent HIV-1 RT-inhibitors. 152
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 151
ANTICONVULSANT ACTIVITY OF PYRROLO[1',2'-1,2]IMIDAZO[4,5- B]PYRIDINES, PYRROLO[2',1'-2,3]IMIDAZO[4,5-C] PYRIDINES AND PYRROLO[2,1-F]PURINES IN DBA/2 MICE 151
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 150
Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile 147
Synthesis and metabolic study of 1H,3H-oxazolo[3,4-a]benzimidazoles, a new class of non-nucleoside HIV-1 RT-inhibitors. 146
OPTIMIZED ENANTIOSELECTIVE HPLC METHOD FOR THE ANALYSIS OF TETRAHYDROISOQUINOLINES 146
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell'integrasi dell'HIV-1. 146
Nuovi Antagonisti Noncompetitivi del Recettore AMPA a struttura tetraidroisochinolinica, 145
PROGETTAZIONE E SINTESI DI NUOVI DERIVATI ISOCHINOLINICI COME AGENTI ANTICONVULSIVANTI MULTITARGET 145
New indole derivatives as promising ligands for ifenprodil site of NR2B/NMDA receptors 145
Discovery of potent HIV-1 integrase strand transfer inhibitors: design and synthetic strategies 144
HIV-1 integrase strand-transfer inhibitors: design and synthetic strategies in the process of a lead optimization 144
Synthesis, Structure-Activity Relationship Studies, and X-ray Crystallographic Analysis of Arylsulfonamides as Potent Carbonic Anhydrase Inhibitors. 144
Development of 3-substituted-1H-indole derivatives as NR2B/NMDA receptor antagonists 144
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series 143
COMPUTATIONAL APPROACHES IN DISCOVERING NOVEL ANTI-AIDS AGENTS 143
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones 143
Computational and synthetic approaches for the discovery of HIV-1 integrase inhibitors 143
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL'INTEGRASI DELL'HIV-1 143
Discovery of HIV-1 Integrase and cellular cofactor LEDGF/p75 interaction inhibitors 143
Derivati benzimidazolonici ed analoghi come potenti inibitori non-nucleosidici dell'RT dell'HIV-1 143
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin- 4-(thi)one derivatives 142
Efficient 3D Database screening for novel HIV-1 IN inhibitors 142
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 142
Insight into the INSTIs binding mode: molecular modeling investigation and SAR studies 142
Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation 142
Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides. 142
Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides 141
Anti-HIV agents .4. Synthesis and in vitro anti-HIV activity of novel 1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4- a]benzimidazoles 139
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 138
Totale 21.934
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Categoria #
all - tutte 148.190
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 148.190
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.502 0 0 0 59 108 9 132 76 37 25 367 689
2022/20235.684 471 420 263 419 502 616 118 341 2.258 17 217 42
2023/20241.285 109 219 85 224 120 208 24 64 2 109 34 87
2024/20255.986 103 96 163 373 243 208 56 1.443 1.579 283 460 979
2025/202621.372 595 2.455 4.338 1.326 1.357 4.174 2.062 2.052 1.997 575 241 200
2026/20272.826 265 750 776 1.035 0 0 0 0 0 0 0 0
Totale 46.749