IRIS
CHIMIRRI, Alba
 Distribuzione geografica
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Continente #
NA - Nord America 18.513
EU - Europa 15.366
AS - Asia 7.795
SA - Sud America 2.720
AF - Africa 232
Continente sconosciuto - Info sul continente non disponibili 194
OC - Oceania 11
Totale 44.831
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Nazione #
US - Stati Uniti d'America 18.220
RU - Federazione Russa 7.827
SG - Singapore 3.312
BR - Brasile 2.352
CN - Cina 2.047
IE - Irlanda 1.819
SE - Svezia 1.570
UA - Ucraina 1.112
VN - Vietnam 837
DE - Germania 801
HK - Hong Kong 734
GB - Regno Unito 497
IT - Italia 461
FR - Francia 435
FI - Finlandia 429
IN - India 240
CA - Canada 139
AR - Argentina 138
BD - Bangladesh 84
MX - Messico 82
PL - Polonia 73
IQ - Iraq 71
TR - Turchia 69
EC - Ecuador 62
CZ - Repubblica Ceca 60
JP - Giappone 54
ZA - Sudafrica 54
AT - Austria 50
MA - Marocco 50
NL - Olanda 45
UZ - Uzbekistan 44
BE - Belgio 43
CO - Colombia 42
ES - Italia 40
CI - Costa d'Avorio 34
ID - Indonesia 32
PK - Pakistan 31
VE - Venezuela 29
IR - Iran 28
CL - Cile 25
PY - Paraguay 22
UY - Uruguay 21
SA - Arabia Saudita 20
JO - Giordania 19
EG - Egitto 18
KE - Kenya 18
TN - Tunisia 18
AE - Emirati Arabi Uniti 17
IL - Israele 17
NP - Nepal 17
PE - Perù 17
KG - Kirghizistan 13
JM - Giamaica 12
OM - Oman 12
BO - Bolivia 11
KZ - Kazakistan 11
LV - Lettonia 11
AL - Albania 10
AZ - Azerbaigian 10
PH - Filippine 10
CH - Svizzera 9
CR - Costa Rica 9
DZ - Algeria 9
HN - Honduras 9
KR - Corea 9
LB - Libano 9
TT - Trinidad e Tobago 9
DO - Repubblica Dominicana 8
LT - Lituania 7
MY - Malesia 7
NZ - Nuova Zelanda 7
PA - Panama 7
A2 - ???statistics.table.value.countryCode.A2??? 6
AO - Angola 6
BG - Bulgaria 6
GR - Grecia 6
NI - Nicaragua 6
RO - Romania 6
SN - Senegal 6
BY - Bielorussia 5
CY - Cipro 5
HU - Ungheria 5
KW - Kuwait 5
MD - Moldavia 5
RS - Serbia 5
SV - El Salvador 5
XK - ???statistics.table.value.countryCode.XK??? 5
AU - Australia 4
ET - Etiopia 4
GE - Georgia 4
LU - Lussemburgo 4
NO - Norvegia 4
PS - Palestinian Territory 4
PT - Portogallo 4
SK - Slovacchia (Repubblica Slovacca) 4
BA - Bosnia-Erzegovina 3
BH - Bahrain 3
DK - Danimarca 3
EE - Estonia 3
EU - Europa 3
Totale 44.604
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Città #
Dallas 5.696
Moscow 2.319
Jacksonville 2.076
Singapore 1.816
Dublin 1.815
Chandler 1.403
Ashburn 1.385
Nyköping 1.010
Beijing 765
Hong Kong 734
Council Bluffs 545
San Jose 532
Dong Ket 505
Los Angeles 363
Cambridge 357
Princeton 354
The Dalles 338
Dearborn 333
Lauterbourg 305
Medford 300
Des Moines 274
Boardman 233
Buffalo 168
Ann Arbor 150
São Paulo 146
Lancaster 130
Ho Chi Minh City 111
Woodbridge 111
New York 106
Columbus 101
Wilmington 96
Guangzhou 87
Tianjin 84
Belo Horizonte 76
Hanoi 75
Jinan 73
Hyderabad 68
San Mateo 68
Orem 66
Nanjing 65
Brooklyn 57
Santa Clara 57
Pune 56
Warsaw 55
Munich 53
Frankfurt am Main 52
Houston 51
Messina 51
Milan 51
Rio de Janeiro 51
Redondo Beach 48
Shenyang 48
Brno 47
Montreal 45
Vienna 44
Chicago 43
Tashkent 42
Tokyo 42
Brasília 41
Brussels 39
Haikou 39
Baghdad 37
Denver 36
Phoenix 36
Abidjan 34
London 34
Seattle 34
Turku 34
Amsterdam 33
Shanghai 33
Zhengzhou 33
Atlanta 31
Hebei 31
Stockholm 31
Johannesburg 30
Campinas 29
Curitiba 29
Manchester 29
San Francisco 27
Catania 26
Ningbo 26
Shenzhen 26
Chennai 25
Nuremberg 24
Washington 24
Goiânia 23
Hangzhou 23
Lappeenranta 23
Poplar 23
Quito 23
Guayaquil 22
Ottawa 22
Porto Alegre 22
Rome 22
Saint Petersburg 22
Augusta 21
Fuzhou 21
Taizhou 21
Mumbai 20
St Petersburg 20
Totale 27.311
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Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 4.616
1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA receptor antagonists 302
1-Phenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 295
1-Aryl-1H,3H-thiazolo[3,4-a]benzimidazole derivatives 286
1,3-THIAZOLIDIN-4-ONES:POTENT AND HIGHLY SELECTIVE ANTI-HIV-1 AGENTS 284
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 276
1-Aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide derivatives: synthesis and biological evaluation 272
1-fluoromethyl-1-methyl-1H,3H-thiazolo-[3,4-a]benzimidazole 270
1H,3H-Thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 241
3,5-dihydro-4H-2,3-benzodiazepine-4-thiones: A new class of AMPA receptor antagonists 212
2-(2,6-dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors 205
AMPA receptor antagonists: Synthesis and pharmacological evaluation 205
2-Hydroxyisoquinoline-1,3(2H,4H)-diones as inhibitors of HIV-1 integrase and reverse transcriptase RNase H domain: Influence of the alkylation of position 4 203
5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice. 194
3H-AZIRINO[1,2-D][1,4]BENZODIAZEPIN-4 (5H)-ONES - SYNTHESIS AND STEREOCHEMISTRY 193
Anticonvulsant activity of azirino[1,2-d][1,4]benzodiazepines and related 1,4-benzodiazepines in mice 192
5H-[1,2,4]OXADIAZOLO[5,4-D][1,5]BENZOTHIAZEPINES - SYNTHESIS AND STEREOCHEMISTRY 191
3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]1,3-oxazolidin-2-one 191
4-[1-(4-Fluorobenzyl)-4-hydroxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid as a prototype to develop dual inhibitors of HIV-1 integration process. 191
Molecular dynamics studies of the wild-type and double mutant HIV-1 integrase complexed with the 5CITEP inhibitor: Mechanism for inhibition and drug resistance 189
Identification of Potent and Selective Human Carbonic Anhydrase VII (hCA VII) Inhibitors 187
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 186
3D Pharmacophore model and synthesys of NMDA receptor subunit NR2B antagonists 184
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 182
Design and synthesis of acetylcholinesterase inhibitors 179
Anti-HIV agents: design and discovery of new potent RT inhibitors 175
Comparative molecular field analysis (CoMFA) and docking studies of non-nucleoside HIV-1 RT inhibitors (NNIs) 174
A new potential approach to block HIV-1 replication via protein–protein interaction and strand-transfer inhibition 173
Azirino[1,2-d][1,4]benzodiazepine derivatives and related 1,4- benzodiazepines as anticonvulsant agents in DBA/2 mice 173
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 172
Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(4 '-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline AMPAR antagonists 170
HIV-1 integrase strand-transfer inhibitors: Design, synthesis and molecular modeling investigation 170
7,11b-dihydro-9,10-dimethoxy-3,11b- diphenyl[1,2,4]oxadiazolo[5,4-a]-[2,3]benzodiazepin-6(5H)-one 167
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 166
Antiretroviral strategy using multi-target agents 166
3D Pharmacophore Models for 1,2,3,4-Tetrahydroisoquinoline Derivatives Acting as Anticonvulsant Agents 166
Microwave-assisted synthesis of benzimidazole and thiazolidinone derivatives as HIV-1 RT inhibitors 164
Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor. 164
Identification of isoquinoline-sulfonamides as potent and selective carbonic anhydrase inhibitors 164
DISCOVERY OF NEW INDOLE DERIVATES AS NEUROPROTECTIVE AGENTS 164
Combined strategies for the discovery of ionotropic glutamate receptor antagonists 162
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 162
Discovery of potent and selective inhibitors of druggable carbonic anhydrase isoforms 162
Inhibitors of the Interactions between HIV-1 IN and the Cofactor LEDGF/p75 162
Sintesi ed attività anti-HIV di 1H,3H-tiazolo[3,4-a]benzimidazoli-sostituiti 161
2-Acetil-1-(4'-clorofenil)-6,7-dimetossi-1,2,3,4-tetraidroisochinolina (Ps3Ac) Potente AMPA-antagonista: Definizione del Profilo Enantiofarmacobiologico 161
Anticonvulsant activity and plasma level of 2,3-benzodiazepin- 4-ones (CFMs) in genetically epilepsy-prone rats 160
Combined ligand-based and target-based approach to design NR2B/NMDA receptor antagonists 160
Analysis of the full-length integrase-DNA complex by a modified approach for DNA docking 159
Modificazioni strutturali del gruppo dichetoacido (DKA) di potenti inibitori dell'Integrasi dell'HIV-1 159
Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as Potent Carbonic Anhydrase Inhibitors: Synthesis, Biological Evaluation, and Enzyme−Ligand X-ray Studies 159
Novel Potent Anticonvulsant Agent Containing a Tetrahydroisoquinoline Skeleton. 158
Compounds with potential anti-tumor activity VII. Synthesis and anti-tumor activity of 1-aryl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines 157
From NMDA receptor antagonists to discovery of selective σ2 receptor ligands 157
Binding modes of noncompetitive AMPA antagonists: a computational approach 156
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 155
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT 155
Antiretroviral strategy: design and synthesis of HIV-1 IN-LEDGF/p75 interaction inhibitors 155
Nuovi selettivi inibitori dell'anidrasi carbonica: sintesi, SAR e studi sull'interazione enzima/inibitore 155
Nuovi ligandi del recettore NR2B/NMDA a struttura indolica 154
Optimization of a LC method for the enantio separation of a non-competitive glutamate receptor antagonist, by experimental design methodology 152
Synthesis and structure-active relationship of 1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline anticonvulsants 152
Binding mode investigation and SAR studies of HIV-1 integrase inhibitors 152
Annelated 1,5-benzothiazepines 152
ANNELATED 1,5-BENZODIAZEPINES .1. 3-MEMBERED, 4-MEMBERED, AND 5-MEMBERED RINGS. 151
Anticonvulsant activity of tetrahydroisoquinoline derivatives as potential new AMPA receptor antagonists 149
ANNELATED 1,5-BENZODIAZEPINES .2. 6 MEMBERED RINGS 149
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL’INTEGRASI DELL’HIV-1 148
Small Molecules Targeting Protein–Protein Interactions: A Promising Anti-HIV Strategy 148
Design and synthesis of 2,3-diaryl-1,3-thiazolidin-4one potent HIV-1 RT-inhibitors. 147
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell'integrasi dell'HIV-1. 144
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 144
ANTICONVULSANT ACTIVITY OF PYRROLO[1',2'-1,2]IMIDAZO[4,5- B]PYRIDINES, PYRROLO[2',1'-2,3]IMIDAZO[4,5-C] PYRIDINES AND PYRROLO[2,1-F]PURINES IN DBA/2 MICE 143
OPTIMIZED ENANTIOSELECTIVE HPLC METHOD FOR THE ANALYSIS OF TETRAHYDROISOQUINOLINES 142
Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile 142
Synthesis and metabolic study of 1H,3H-oxazolo[3,4-a]benzimidazoles, a new class of non-nucleoside HIV-1 RT-inhibitors. 141
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL'INTEGRASI DELL'HIV-1 141
Nuovi Antagonisti Noncompetitivi del Recettore AMPA a struttura tetraidroisochinolinica, 140
Computational and synthetic approaches for the discovery of HIV-1 integrase inhibitors 140
Discovery of HIV-1 Integrase and cellular cofactor LEDGF/p75 interaction inhibitors 140
Discovery of potent HIV-1 integrase strand transfer inhibitors: design and synthetic strategies 140
HIV-1 integrase strand-transfer inhibitors: design and synthetic strategies in the process of a lead optimization 140
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 139
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones 139
PROGETTAZIONE E SINTESI DI NUOVI DERIVATI ISOCHINOLINICI COME AGENTI ANTICONVULSIVANTI MULTITARGET 139
Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation 139
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 138
Derivati benzimidazolonici ed analoghi come potenti inibitori non-nucleosidici dell'RT dell'HIV-1 138
COMPUTATIONAL APPROACHES IN DISCOVERING NOVEL ANTI-AIDS AGENTS 137
Efficient 3D Database screening for novel HIV-1 IN inhibitors 137
Insight into the INSTIs binding mode: molecular modeling investigation and SAR studies 137
Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides. 137
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series 136
New indole derivatives as promising ligands for ifenprodil site of NR2B/NMDA receptors 136
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin- 4-(thi)one derivatives 135
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 135
Computational studies and synthetic approaches for the identification of new protein-protein interaction inhibitors (PPI) 135
Synthesis, Structure-Activity Relationship Studies, and X-ray Crystallographic Analysis of Arylsulfonamides as Potent Carbonic Anhydrase Inhibitors. 135
An unexpected reaction between 2,3-dihydro-2,2,4-trimethyl-1H-1,5-benzodiazepine and mercaptoacetic acid 135
Development of 3-substituted-1H-indole derivatives as NR2B/NMDA receptor antagonists 135
Totale 21.282
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Categoria #
all - tutte 140.400
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 140.400
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.889 0 339 48 59 108 9 132 76 37 25 367 689
2022/20235.684 471 420 263 419 502 616 118 341 2.258 17 217 42
2023/20241.285 109 219 85 224 120 208 24 64 2 109 34 87
2024/20255.986 103 96 163 373 243 208 56 1.443 1.579 283 460 979
2025/202621.372 595 2.455 4.338 1.326 1.357 4.174 2.062 2.052 1.997 575 241 200
2026/2027908 265 643 0 0 0 0 0 0 0 0 0 0
Totale 44.831