IRIS
CHIMIRRI, Alba
 Distribuzione geografica
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Continente #
NA - Nord America 17.639
EU - Europa 15.328
AS - Asia 7.782
SA - Sud America 2.688
AF - Africa 232
Continente sconosciuto - Info sul continente non disponibili 14
OC - Oceania 11
Totale 43.694
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Nazione #
US - Stati Uniti d'America 17.377
RU - Federazione Russa 7.826
SG - Singapore 3.309
BR - Brasile 2.335
CN - Cina 2.038
IE - Irlanda 1.819
SE - Svezia 1.570
UA - Ucraina 1.110
VN - Vietnam 836
DE - Germania 801
HK - Hong Kong 734
GB - Regno Unito 497
IT - Italia 442
FR - Francia 431
FI - Finlandia 429
IN - India 240
AR - Argentina 132
CA - Canada 125
BD - Bangladesh 84
MX - Messico 78
PL - Polonia 72
IQ - Iraq 71
TR - Turchia 69
CZ - Repubblica Ceca 60
EC - Ecuador 57
JP - Giappone 54
ZA - Sudafrica 54
AT - Austria 50
MA - Marocco 50
NL - Olanda 45
UZ - Uzbekistan 44
BE - Belgio 43
CO - Colombia 41
CI - Costa d'Avorio 34
ES - Italia 33
ID - Indonesia 32
PK - Pakistan 31
VE - Venezuela 29
IR - Iran 28
CL - Cile 24
PY - Paraguay 22
UY - Uruguay 21
SA - Arabia Saudita 20
JO - Giordania 19
EG - Egitto 18
KE - Kenya 18
TN - Tunisia 18
AE - Emirati Arabi Uniti 17
IL - Israele 17
NP - Nepal 17
PE - Perù 16
KG - Kirghizistan 13
OM - Oman 12
KZ - Kazakistan 11
AL - Albania 10
AZ - Azerbaigian 10
BO - Bolivia 10
LV - Lettonia 10
PH - Filippine 10
CH - Svizzera 9
DZ - Algeria 9
KR - Corea 9
LB - Libano 9
CR - Costa Rica 8
DO - Repubblica Dominicana 8
HN - Honduras 8
JM - Giamaica 8
LT - Lituania 7
MY - Malesia 7
NZ - Nuova Zelanda 7
A2 - ???statistics.table.value.countryCode.A2??? 6
AO - Angola 6
BG - Bulgaria 6
GR - Grecia 6
NI - Nicaragua 6
PA - Panama 6
SN - Senegal 6
TT - Trinidad e Tobago 6
CY - Cipro 5
HU - Ungheria 5
KW - Kuwait 5
MD - Moldavia 5
RO - Romania 5
RS - Serbia 5
XK - ???statistics.table.value.countryCode.XK??? 5
AU - Australia 4
BY - Bielorussia 4
ET - Etiopia 4
GE - Georgia 4
LU - Lussemburgo 4
NO - Norvegia 4
PS - Palestinian Territory 4
PT - Portogallo 4
SK - Slovacchia (Repubblica Slovacca) 4
BA - Bosnia-Erzegovina 3
BH - Bahrain 3
EE - Estonia 3
EU - Europa 3
GA - Gabon 3
GT - Guatemala 3
Totale 43.649
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Città #
Dallas 5.694
Moscow 2.319
Jacksonville 2.075
Dublin 1.815
Singapore 1.814
Chandler 1.403
Ashburn 1.359
Nyköping 1.010
Beijing 764
Hong Kong 734
Dong Ket 505
San Jose 492
Los Angeles 359
Cambridge 357
Princeton 354
The Dalles 338
Dearborn 333
Lauterbourg 305
Medford 300
Des Moines 274
Boardman 233
Buffalo 167
Ann Arbor 150
São Paulo 145
Council Bluffs 132
Lancaster 130
Ho Chi Minh City 111
Woodbridge 110
New York 104
Wilmington 96
Guangzhou 87
Tianjin 84
Belo Horizonte 76
Hanoi 74
Jinan 73
Hyderabad 68
San Mateo 68
Orem 66
Nanjing 65
Pune 56
Brooklyn 55
Warsaw 55
Munich 53
Frankfurt am Main 52
Messina 51
Rio de Janeiro 50
Houston 49
Milan 49
Redondo Beach 48
Shenyang 48
Brno 47
Santa Clara 44
Vienna 44
Montreal 43
Tashkent 42
Tokyo 42
Brasília 41
Brussels 39
Haikou 39
Chicago 38
Baghdad 37
Denver 36
Abidjan 34
London 34
Seattle 34
Turku 34
Amsterdam 33
Phoenix 33
Shanghai 33
Zhengzhou 33
Hebei 31
Stockholm 31
Johannesburg 30
Atlanta 29
Campinas 29
Curitiba 29
Manchester 29
San Francisco 27
Catania 26
Ningbo 26
Shenzhen 26
Chennai 25
Nuremberg 24
Goiânia 23
Hangzhou 23
Lappeenranta 23
Poplar 23
Washington 23
Ottawa 22
Porto Alegre 22
Quito 22
Saint Petersburg 22
Augusta 21
Fuzhou 21
Taizhou 21
Guayaquil 20
Mumbai 20
Toronto 20
Ardabil 19
Dhaka 19
Totale 26.695
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Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 4.608
1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA receptor antagonists 298
1-Phenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 291
1-Aryl-1H,3H-thiazolo[3,4-a]benzimidazole derivatives 282
1,3-THIAZOLIDIN-4-ONES:POTENT AND HIGHLY SELECTIVE ANTI-HIV-1 AGENTS 280
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 271
1-fluoromethyl-1-methyl-1H,3H-thiazolo-[3,4-a]benzimidazole 269
1-Aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide derivatives: synthesis and biological evaluation 268
1H,3H-Thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 240
3,5-dihydro-4H-2,3-benzodiazepine-4-thiones: A new class of AMPA receptor antagonists 210
AMPA receptor antagonists: Synthesis and pharmacological evaluation 203
2-(2,6-dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors 202
2-Hydroxyisoquinoline-1,3(2H,4H)-diones as inhibitors of HIV-1 integrase and reverse transcriptase RNase H domain: Influence of the alkylation of position 4 196
3H-AZIRINO[1,2-D][1,4]BENZODIAZEPIN-4 (5H)-ONES - SYNTHESIS AND STEREOCHEMISTRY 192
5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice. 192
5H-[1,2,4]OXADIAZOLO[5,4-D][1,5]BENZOTHIAZEPINES - SYNTHESIS AND STEREOCHEMISTRY 190
3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]1,3-oxazolidin-2-one 190
4-[1-(4-Fluorobenzyl)-4-hydroxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid as a prototype to develop dual inhibitors of HIV-1 integration process. 190
Anticonvulsant activity of azirino[1,2-d][1,4]benzodiazepines and related 1,4-benzodiazepines in mice 189
3D Pharmacophore model and synthesys of NMDA receptor subunit NR2B antagonists 183
Identification of Potent and Selective Human Carbonic Anhydrase VII (hCA VII) Inhibitors 182
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 181
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 178
Design and synthesis of acetylcholinesterase inhibitors 177
Anti-HIV agents: design and discovery of new potent RT inhibitors 172
A new potential approach to block HIV-1 replication via protein–protein interaction and strand-transfer inhibition 172
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 171
Azirino[1,2-d][1,4]benzodiazepine derivatives and related 1,4- benzodiazepines as anticonvulsant agents in DBA/2 mice 170
Comparative molecular field analysis (CoMFA) and docking studies of non-nucleoside HIV-1 RT inhibitors (NNIs) 168
Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(4 '-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline AMPAR antagonists 167
HIV-1 integrase strand-transfer inhibitors: Design, synthesis and molecular modeling investigation 166
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 165
7,11b-dihydro-9,10-dimethoxy-3,11b- diphenyl[1,2,4]oxadiazolo[5,4-a]-[2,3]benzodiazepin-6(5H)-one 164
Antiretroviral strategy using multi-target agents 164
3D Pharmacophore Models for 1,2,3,4-Tetrahydroisoquinoline Derivatives Acting as Anticonvulsant Agents 163
Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor. 162
Microwave-assisted synthesis of benzimidazole and thiazolidinone derivatives as HIV-1 RT inhibitors 161
Combined strategies for the discovery of ionotropic glutamate receptor antagonists 161
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 161
DISCOVERY OF NEW INDOLE DERIVATES AS NEUROPROTECTIVE AGENTS 161
Sintesi ed attività anti-HIV di 1H,3H-tiazolo[3,4-a]benzimidazoli-sostituiti 160
Discovery of potent and selective inhibitors of druggable carbonic anhydrase isoforms 160
Identification of isoquinoline-sulfonamides as potent and selective carbonic anhydrase inhibitors 160
Inhibitors of the Interactions between HIV-1 IN and the Cofactor LEDGF/p75 160
2-Acetil-1-(4'-clorofenil)-6,7-dimetossi-1,2,3,4-tetraidroisochinolina (Ps3Ac) Potente AMPA-antagonista: Definizione del Profilo Enantiofarmacobiologico 160
Combined ligand-based and target-based approach to design NR2B/NMDA receptor antagonists 159
Modificazioni strutturali del gruppo dichetoacido (DKA) di potenti inibitori dell'Integrasi dell'HIV-1 158
Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as Potent Carbonic Anhydrase Inhibitors: Synthesis, Biological Evaluation, and Enzyme−Ligand X-ray Studies 158
Novel Potent Anticonvulsant Agent Containing a Tetrahydroisoquinoline Skeleton. 157
Anticonvulsant activity and plasma level of 2,3-benzodiazepin- 4-ones (CFMs) in genetically epilepsy-prone rats 156
Analysis of the full-length integrase-DNA complex by a modified approach for DNA docking 156
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT 153
Nuovi ligandi del recettore NR2B/NMDA a struttura indolica 153
Nuovi selettivi inibitori dell'anidrasi carbonica: sintesi, SAR e studi sull'interazione enzima/inibitore 153
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 152
Antiretroviral strategy: design and synthesis of HIV-1 IN-LEDGF/p75 interaction inhibitors 152
From NMDA receptor antagonists to discovery of selective σ2 receptor ligands 152
Compounds with potential anti-tumor activity VII. Synthesis and anti-tumor activity of 1-aryl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines 151
Binding modes of noncompetitive AMPA antagonists: a computational approach 151
Optimization of a LC method for the enantio separation of a non-competitive glutamate receptor antagonist, by experimental design methodology 151
Binding mode investigation and SAR studies of HIV-1 integrase inhibitors 151
Annelated 1,5-benzothiazepines 151
Synthesis and structure-active relationship of 1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline anticonvulsants 150
ANNELATED 1,5-BENZODIAZEPINES .1. 3-MEMBERED, 4-MEMBERED, AND 5-MEMBERED RINGS. 149
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL’INTEGRASI DELL’HIV-1 147
ANNELATED 1,5-BENZODIAZEPINES .2. 6 MEMBERED RINGS 147
Small Molecules Targeting Protein–Protein Interactions: A Promising Anti-HIV Strategy 146
Anticonvulsant activity of tetrahydroisoquinoline derivatives as potential new AMPA receptor antagonists 145
Design and synthesis of 2,3-diaryl-1,3-thiazolidin-4one potent HIV-1 RT-inhibitors. 145
ANTICONVULSANT ACTIVITY OF PYRROLO[1',2'-1,2]IMIDAZO[4,5- B]PYRIDINES, PYRROLO[2',1'-2,3]IMIDAZO[4,5-C] PYRIDINES AND PYRROLO[2,1-F]PURINES IN DBA/2 MICE 142
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell'integrasi dell'HIV-1. 141
OPTIMIZED ENANTIOSELECTIVE HPLC METHOD FOR THE ANALYSIS OF TETRAHYDROISOQUINOLINES 140
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL'INTEGRASI DELL'HIV-1 140
Synthesis and metabolic study of 1H,3H-oxazolo[3,4-a]benzimidazoles, a new class of non-nucleoside HIV-1 RT-inhibitors. 139
Computational and synthetic approaches for the discovery of HIV-1 integrase inhibitors 139
Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile 139
Discovery of HIV-1 Integrase and cellular cofactor LEDGF/p75 interaction inhibitors 139
Discovery of potent HIV-1 integrase strand transfer inhibitors: design and synthetic strategies 139
PROGETTAZIONE E SINTESI DI NUOVI DERIVATI ISOCHINOLINICI COME AGENTI ANTICONVULSIVANTI MULTITARGET 138
Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation 138
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 137
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones 137
Nuovi Antagonisti Noncompetitivi del Recettore AMPA a struttura tetraidroisochinolinica, 137
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 137
HIV-1 integrase strand-transfer inhibitors: design and synthetic strategies in the process of a lead optimization 137
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 136
Derivati benzimidazolonici ed analoghi come potenti inibitori non-nucleosidici dell'RT dell'HIV-1 136
Insight into the INSTIs binding mode: molecular modeling investigation and SAR studies 136
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series 135
Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides. 135
COMPUTATIONAL APPROACHES IN DISCOVERING NOVEL ANTI-AIDS AGENTS 134
Efficient 3D Database screening for novel HIV-1 IN inhibitors 134
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin- 4-(thi)one derivatives 133
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 133
Computational studies and synthetic approaches for the identification of new protein-protein interaction inhibitors (PPI) 133
New indole derivatives as promising ligands for ifenprodil site of NR2B/NMDA receptors 133
Development of 3-substituted-1H-indole derivatives as NR2B/NMDA receptor antagonists 133
Synthesis, Structure-Activity Relationship Studies, and X-ray Crystallographic Analysis of Arylsulfonamides as Potent Carbonic Anhydrase Inhibitors. 132
Progettazione, Sintesi e SAR di analoghi 1,3-diidro-benzimidazoloni come nuovi agenti anti-HIV 131
Anti-HIV agents .4. Synthesis and in vitro anti-HIV activity of novel 1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4- a]benzimidazoles 131
Totale 20.977
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Categoria #
all - tutte 135.082
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 135.082
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021622 0 0 0 0 0 0 0 0 0 0 0 622
2021/20221.911 22 339 48 59 108 9 132 76 37 25 367 689
2022/20235.684 471 420 263 419 502 616 118 341 2.258 17 217 42
2023/20241.285 109 219 85 224 120 208 24 64 2 109 34 87
2024/20255.986 103 96 163 373 243 208 56 1.443 1.579 283 460 979
2025/202621.323 595 2.455 4.338 1.326 1.357 4.174 2.062 2.052 1.997 575 241 151
Totale 43.874