IRIS
DE LUCA, Laura
 Distribuzione geografica
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Continente #
NA - Nord America 19.091
EU - Europa 14.965
AS - Asia 7.322
SA - Sud America 2.587
Continente sconosciuto - Info sul continente non disponibili 424
AF - Africa 228
OC - Oceania 12
Totale 44.629
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Nazione #
US - Stati Uniti d'America 18.636
RU - Federazione Russa 7.857
SG - Singapore 3.092
BR - Brasile 2.225
CN - Cina 1.975
IE - Irlanda 1.739
SE - Svezia 1.439
IT - Italia 937
HK - Hong Kong 757
UA - Ucraina 710
DE - Germania 634
VN - Vietnam 557
FR - Francia 415
GB - Regno Unito 381
FI - Finlandia 359
IN - India 258
CA - Canada 185
AR - Argentina 132
BD - Bangladesh 109
MX - Messico 98
PL - Polonia 89
CZ - Repubblica Ceca 75
IQ - Iraq 68
TR - Turchia 68
ZA - Sudafrica 60
JP - Giappone 59
EC - Ecuador 56
BE - Belgio 55
NL - Olanda 51
ES - Italia 47
MA - Marocco 46
AT - Austria 45
UZ - Uzbekistan 44
ID - Indonesia 38
VE - Venezuela 37
CO - Colombia 35
PK - Pakistan 35
CL - Cile 27
CI - Costa d'Avorio 26
CR - Costa Rica 26
PY - Paraguay 25
IL - Israele 23
SA - Arabia Saudita 23
KE - Kenya 22
AE - Emirati Arabi Uniti 21
EG - Egitto 21
HN - Honduras 21
GT - Guatemala 18
JM - Giamaica 18
JO - Giordania 18
PE - Perù 18
UY - Uruguay 17
AZ - Azerbaigian 16
GR - Grecia 15
NI - Nicaragua 15
PH - Filippine 15
IR - Iran 14
NP - Nepal 14
BO - Bolivia 13
CW - ???statistics.table.value.countryCode.CW??? 13
MY - Malesia 13
NO - Norvegia 13
TT - Trinidad e Tobago 13
GP - Guadalupe 12
LV - Lettonia 12
OM - Oman 12
KG - Kirghizistan 11
PA - Panama 11
PR - Porto Rico 11
PS - Palestinian Territory 11
DO - Repubblica Dominicana 10
DZ - Algeria 10
KZ - Kazakistan 10
RO - Romania 10
AL - Albania 9
EE - Estonia 9
LK - Sri Lanka 9
LT - Lituania 9
TN - Tunisia 8
AM - Armenia 7
CH - Svizzera 7
LB - Libano 7
PT - Portogallo 7
SK - Slovacchia (Repubblica Slovacca) 7
AU - Australia 6
RS - Serbia 6
SC - Seychelles 6
SV - El Salvador 6
KR - Corea 5
MD - Moldavia 5
NZ - Nuova Zelanda 5
SN - Senegal 5
SY - Repubblica araba siriana 5
XK - ???statistics.table.value.countryCode.XK??? 5
A2 - ???statistics.table.value.countryCode.A2??? 4
AO - Angola 4
BY - Bielorussia 4
ET - Etiopia 4
GA - Gabon 4
GE - Georgia 4
Totale 44.158
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Città #
Dallas 5.591
Moscow 2.251
Ashburn 1.936
Dublin 1.735
Singapore 1.652
Jacksonville 1.330
Chandler 1.322
Nyköping 945
San Jose 775
Hong Kong 754
Beijing 719
Council Bluffs 587
Los Angeles 343
The Dalles 339
Princeton 298
Medford 258
Cambridge 256
Dearborn 256
Lauterbourg 252
Des Moines 230
Messina 230
Dong Ket 186
Boardman 172
Ann Arbor 158
São Paulo 151
Buffalo 142
Ho Chi Minh City 124
Munich 118
New York 118
Santa Clara 91
Hyderabad 87
Guangzhou 86
Wilmington 84
Woodbridge 80
Tianjin 78
Orem 75
Hanoi 73
Lancaster 69
Redondo Beach 69
Warsaw 66
Belo Horizonte 65
Brooklyn 65
Phoenix 65
Milan 63
Columbus 60
Pune 60
Jinan 58
Turku 57
Brno 56
Chicago 55
Rio de Janeiro 54
Frankfurt am Main 53
San Mateo 52
Atlanta 51
Montreal 51
Shenyang 51
Brussels 49
Denver 49
Tokyo 48
Brasília 47
Nanjing 46
Catania 45
Rome 45
London 44
Seattle 44
Tashkent 42
Houston 39
Johannesburg 37
Shanghai 35
Haikou 33
Lappeenranta 33
Vienna 33
Nuremberg 31
Curitiba 29
Hebei 29
Manchester 29
Baghdad 28
Chennai 28
San Francisco 27
Stockholm 27
Taizhou 27
Toronto 27
Abidjan 26
Hangzhou 25
Shenzhen 25
Turin 25
Washington 25
Amsterdam 24
Goiânia 24
Mexico City 24
Zhengzhou 23
Da Nang 22
Poplar 22
San José 22
Campinas 21
Guarulhos 21
Guayaquil 21
Naples 21
Ningbo 21
Porto Alegre 21
Totale 26.366
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Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 4.625
1,3-THIAZOLIDIN-4-ONES:POTENT AND HIGHLY SELECTIVE ANTI-HIV-1 AGENTS 292
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 286
Chemical exploration of 4-(4-fluorobenzyl)piperidine fragment for the development of new tyrosinase inhibitors 266
1-Benzylpiperidine derivatives: design and synthesis of new compounds as tyrosinase inhibitors from Agaricus bisporus 238
Inhibition of HIV-1 RT activity by a new series of 3-(1,3,4-thiadiazol-2-yl)thiazolidin-4-one derivatives 236
4-Fluorobenzylpiperazine-Containing Derivatives as Efficient Inhibitors of Mushroom Tyrosinase 223
Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases 221
Anticonvulsant agent: enhancement of physicochemical properties 214
2-Hydroxyisoquinoline-1,3(2H,4H)-diones as inhibitors of HIV-1 integrase and reverse transcriptase RNase H domain: Influence of the alkylation of position 4 212
AMPA receptor antagonists: Synthesis and pharmacological evaluation 212
A Combination of Pharmacophore and Docking-based Virtual Screening to Discover new Tyrosinase Inhibitors 212
Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile 210
Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments 210
4-[1-(4-Fluorobenzyl)-4-hydroxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid as a prototype to develop dual inhibitors of HIV-1 integration process. 201
Computational methods to analyze and predict the binding mode of inhibitors targeting both human and mushroom tyrosinase 200
Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives 200
P158-DEVELOPMENT OF FLEXIBLE ARYLSULFONAMIDES AS POTENTIAL MULTITARGET ANTICANCER AGENTS 199
Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety 197
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 196
Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms 196
4-Sulfamoylphenylalkylamides as Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae 196
InVivo Evaluation of Selective Carbonic Anhydrase Inhibitors as Potential Anticonvulsant Agents 195
Discovery of a new potent inhibitor of mushroom tyrosinase (Agaricus bisporus) containing 4-(4-hydroxyphenyl)piperazin-1-yl moiety 193
Synthesis and biochemical evaluation of 5-(pyridin-4-yl)-4H-1,2,4-triazol-4-amine-based inhibitors of tyrosinase from Agaricus bisporus 192
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 191
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis 190
3D Pharmacophore model and synthesys of NMDA receptor subunit NR2B antagonists 188
Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms 188
Anti-HIV agents: design and discovery of new potent RT inhibitors 186
Design and optimization of isoquinoline-sulfonamides as potent and selective inhibitors of human carbonic anhydrase VII 186
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 182
Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(4 '-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline AMPAR antagonists 181
Vitamin D: a steroid hormone with progesterone-like activity 181
Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson’s disease 181
6-Chloro-1-(3,5-dimethylphenylsulfonyl)-1H-benzimidazol-2(3H)-one 179
A new potential approach to block HIV-1 replication via protein–protein interaction and strand-transfer inhibition 179
Merging lithium carbenoid homologation and enzymatic reduction: A combinative approach to the HIV-protease inhibitor Nelfinavir 179
HIV-1 integrase strand-transfer inhibitors: Design, synthesis and molecular modeling investigation 178
In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae 178
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 177
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 176
Antiretroviral strategy using multi-target agents 174
Identification of isoquinoline-sulfonamides as potent and selective carbonic anhydrase inhibitors 174
3D Pharmacophore Models for 1,2,3,4-Tetrahydroisoquinoline Derivatives Acting as Anticonvulsant Agents 174
In Silico Strategy for Targeting the mTOR Kinase at Rapamycin Binding Site by Small Molecules 174
Synthesis and biological evaluation of sulfonamide-based compounds as inhibitors of carbonic anhydrase from Vibrio cholerae 173
Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor. 171
Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as Potent Carbonic Anhydrase Inhibitors: Synthesis, Biological Evaluation, and Enzyme−Ligand X-ray Studies 170
Graphene Quantum Dots Based Systems As HIV Inhibitors 170
Analysis of structure-activity relationships in a series of 4-(1-piperazinyl)phenol-based derivatives as competitive inhibitors of Tyrosinase 170
Analysis of the full-length integrase-DNA complex by a modified approach for DNA docking 169
Discovery of potent and selective inhibitors of druggable carbonic anhydrase isoforms 169
Combined ligand-based and target-based approach to design NR2B/NMDA receptor antagonists 168
DISCOVERY OF NEW INDOLE DERIVATES AS NEUROPROTECTIVE AGENTS 168
2-Acetil-1-(4'-clorofenil)-6,7-dimetossi-1,2,3,4-tetraidroisochinolina (Ps3Ac) Potente AMPA-antagonista: Definizione del Profilo Enantiofarmacobiologico 168
Synthesis and anti-HIV activity of carboxylated and drug-conjugated multi-walled carbon nanotubes 167
Binding modes of noncompetitive AMPA antagonists: a computational approach 167
Combined strategies for the discovery of ionotropic glutamate receptor antagonists 167
Novel Potent Anticonvulsant Agent Containing a Tetrahydroisoquinoline Skeleton. 166
Inhibitors of the Interactions between HIV-1 IN and the Cofactor LEDGF/p75 166
Searching for indole derivatives as potential mushroom tyrosinase inhibitors 166
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 166
Evaluation of 4-(4-Fluorobenzyl)piperazin-1-yl]-Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects 166
Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from Agaricus bisporus 165
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 165
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT 164
Modificazioni strutturali del gruppo dichetoacido (DKA) di potenti inibitori dell'Integrasi dell'HIV-1 163
Design, synthesis and in vitro evaluation of 4-fluorobenzyl- and 4-hydroxyphenyl-based compounds targeting tyrosinases 163
From NMDA receptor antagonists to discovery of selective σ2 receptor ligands 162
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 161
Antiretroviral strategy: design and synthesis of HIV-1 IN-LEDGF/p75 interaction inhibitors 161
Synthesis and structure-active relationship of 1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline anticonvulsants 161
Synthesis of new pyridazine derivatives as potential anti-HIV-1 agents 160
Binding mode investigation and SAR studies of HIV-1 integrase inhibitors 159
INVESTIGATION ON PYRIDINYL-1,2,4-TRIAZOLE-BASED COMPOUNDS AS -SYN AGGREGATION INHIBITORS FOR TREATING PARKINSON’S DISEASE 159
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis 157
Small Molecules Targeting Protein–Protein Interactions: A Promising Anti-HIV Strategy 157
Nuovi ligandi del recettore NR2B/NMDA a struttura indolica 156
Structural optimization and in vitro evaluation of new 1-(4-fluorobenzyl)piperazine derivatives as inhibitors of Tyrosinase from Agaricus bisporus 155
Design and synthesis of 2,3-diaryl-1,3-thiazolidin-4one potent HIV-1 RT-inhibitors. 154
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL’INTEGRASI DELL’HIV-1 153
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 152
Probing the molecular interactions between the human Carbonic Anhydrases (hCAs) and a novel class of benzenesulfonamides 151
Ligand-Based Discovery of a Small Molecule as Inhibitor of α-Synuclein Amyloid Formation 150
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 150
Serendipitous discovery of indole derivatives as potent tyrosinase inhibitors 149
The 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors 149
Searching for alpha-syn inhibitors to fight Parkinson’s disease 149
Synthesis, Structure-Activity Relationship Studies, and X-ray Crystallographic Analysis of Arylsulfonamides as Potent Carbonic Anhydrase Inhibitors. 148
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell'integrasi dell'HIV-1. 147
Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile 147
Exploring the chemical space of 3-chloro-4-fluorophenyl-based compounds as tyrosinase inhibitors 146
Computational and synthetic approaches for the discovery of HIV-1 integrase inhibitors 146
Discovery of potent HIV-1 integrase strand transfer inhibitors: design and synthetic strategies 145
HIV-1 integrase strand-transfer inhibitors: design and synthetic strategies in the process of a lead optimization 145
New indole derivatives as promising ligands for ifenprodil site of NR2B/NMDA receptors 145
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series 144
COMPUTATIONAL APPROACHES IN DISCOVERING NOVEL ANTI-AIDS AGENTS 144
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL'INTEGRASI DELL'HIV-1 144
Totale 22.171
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Categoria #
all - tutte 141.235
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 141.235
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.422 0 0 0 0 81 29 163 63 39 67 371 609
2022/20235.186 400 443 235 450 387 508 108 273 2.120 15 185 62
2023/20241.327 96 201 96 244 117 221 24 45 5 116 29 133
2024/20255.947 101 95 110 344 257 195 196 1.385 1.459 332 525 948
2025/202622.003 794 2.469 4.277 1.455 1.402 4.059 2.048 2.199 2.106 679 261 254
2026/20272.859 257 693 725 958 226 0 0 0 0 0 0 0
Totale 44.629