IRIS
DE LUCA, Laura
 Distribuzione geografica
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Continente #
NA - Nord America 16.078
EU - Europa 14.649
AS - Asia 7.167
SA - Sud America 2.559
AF - Africa 219
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 10
Totale 40.694
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Nazione #
US - Stati Uniti d'America 15.831
RU - Federazione Russa 7.836
SG - Singapore 3.062
BR - Brasile 2.212
CN - Cina 1.914
IE - Irlanda 1.738
SE - Svezia 1.439
HK - Hong Kong 746
IT - Italia 719
UA - Ucraina 706
DE - Germania 626
VN - Vietnam 552
FR - Francia 408
FI - Finlandia 359
GB - Regno Unito 357
IN - India 257
AR - Argentina 127
CA - Canada 108
MX - Messico 91
BD - Bangladesh 85
PL - Polonia 85
CZ - Repubblica Ceca 74
IQ - Iraq 68
TR - Turchia 67
ZA - Sudafrica 59
JP - Giappone 58
EC - Ecuador 55
BE - Belgio 53
MA - Marocco 46
NL - Olanda 46
AT - Austria 45
UZ - Uzbekistan 44
ID - Indonesia 37
ES - Italia 36
VE - Venezuela 36
PK - Pakistan 35
CO - Colombia 32
CI - Costa d'Avorio 26
PY - Paraguay 25
CL - Cile 24
SA - Arabia Saudita 23
KE - Kenya 22
EG - Egitto 21
AE - Emirati Arabi Uniti 19
JO - Giordania 18
PE - Perù 17
UY - Uruguay 17
AZ - Azerbaigian 16
GR - Grecia 15
PH - Filippine 15
IR - Iran 14
NO - Norvegia 13
NP - Nepal 13
BO - Bolivia 12
LV - Lettonia 12
MY - Malesia 12
OM - Oman 12
KG - Kirghizistan 11
PS - Palestinian Territory 11
DO - Repubblica Dominicana 10
IL - Israele 10
KZ - Kazakistan 10
PA - Panama 10
RO - Romania 10
AL - Albania 9
DZ - Algeria 9
LK - Sri Lanka 9
HN - Honduras 8
LT - Lituania 8
TN - Tunisia 8
SK - Slovacchia (Repubblica Slovacca) 7
AU - Australia 6
CH - Svizzera 6
JM - Giamaica 6
LB - Libano 6
PT - Portogallo 6
RS - Serbia 6
AM - Armenia 5
EE - Estonia 5
KR - Corea 5
MD - Moldavia 5
NZ - Nuova Zelanda 5
SN - Senegal 5
SY - Repubblica araba siriana 5
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A2 - ???statistics.table.value.countryCode.A2??? 4
AO - Angola 4
CR - Costa Rica 4
ET - Etiopia 4
GE - Georgia 4
GT - Guatemala 4
HU - Ungheria 4
TH - Thailandia 4
TW - Taiwan 4
BG - Bulgaria 3
BH - Bahrain 3
BY - Bielorussia 3
GA - Gabon 3
KW - Kuwait 3
LU - Lussemburgo 3
Totale 40.655
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Città #
Dallas 5.568
Moscow 2.251
Dublin 1.735
Singapore 1.636
Ashburn 1.513
Jacksonville 1.327
Chandler 1.321
Nyköping 945
Hong Kong 743
Beijing 702
San Jose 362
The Dalles 329
Los Angeles 328
Princeton 296
Medford 257
Cambridge 256
Dearborn 256
Lauterbourg 252
Des Moines 228
Messina 228
Dong Ket 186
Boardman 170
Ann Arbor 158
São Paulo 149
Buffalo 134
Ho Chi Minh City 124
Munich 117
New York 105
Hyderabad 87
Guangzhou 86
Wilmington 82
Woodbridge 79
Tianjin 78
Hanoi 71
Orem 71
Lancaster 69
Redondo Beach 69
Belo Horizonte 65
Warsaw 64
Pune 60
Jinan 58
Turku 57
Brno 56
Rio de Janeiro 54
Frankfurt am Main 53
Council Bluffs 52
San Mateo 52
Shenyang 51
Brussels 49
Tokyo 48
Brasília 47
Nanjing 46
Chicago 45
Santa Clara 44
Brooklyn 43
Catania 42
London 42
Tashkent 42
Denver 41
Milan 41
Seattle 40
Johannesburg 37
Phoenix 37
Montreal 36
Atlanta 34
Haikou 33
Lappeenranta 33
Shanghai 33
Vienna 33
Houston 31
Nuremberg 31
Curitiba 29
Hebei 29
Manchester 29
Baghdad 28
Chennai 28
Stockholm 27
Taizhou 27
Abidjan 26
Shenzhen 25
Goiânia 24
Hangzhou 24
Amsterdam 23
Rome 23
Toronto 23
Zhengzhou 23
Poplar 22
Campinas 21
Da Nang 21
Guarulhos 21
Mexico City 21
Ningbo 21
Porto Alegre 21
Washington 21
Boston 20
Düsseldorf 20
Francofonte 20
Guayaquil 20
Helsinki 20
Dhaka 19
Totale 24.574
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Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 4.606
1,3-THIAZOLIDIN-4-ONES:POTENT AND HIGHLY SELECTIVE ANTI-HIV-1 AGENTS 278
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 269
Chemical exploration of 4-(4-fluorobenzyl)piperidine fragment for the development of new tyrosinase inhibitors 253
1-Benzylpiperidine derivatives: design and synthesis of new compounds as tyrosinase inhibitors from Agaricus bisporus 220
4-Fluorobenzylpiperazine-Containing Derivatives as Efficient Inhibitors of Mushroom Tyrosinase 213
Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases 202
AMPA receptor antagonists: Synthesis and pharmacological evaluation 201
Anticonvulsant agent: enhancement of physicochemical properties 195
2-Hydroxyisoquinoline-1,3(2H,4H)-diones as inhibitors of HIV-1 integrase and reverse transcriptase RNase H domain: Influence of the alkylation of position 4 194
Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile 194
Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments 194
Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives 189
4-[1-(4-Fluorobenzyl)-4-hydroxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid as a prototype to develop dual inhibitors of HIV-1 integration process. 187
A Combination of Pharmacophore and Docking-based Virtual Screening to Discover new Tyrosinase Inhibitors 187
Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety 184
Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms 183
Computational methods to analyze and predict the binding mode of inhibitors targeting both human and mushroom tyrosinase 180
InVivo Evaluation of Selective Carbonic Anhydrase Inhibitors as Potential Anticonvulsant Agents 180
Discovery of a new potent inhibitor of mushroom tyrosinase (Agaricus bisporus) containing 4-(4-hydroxyphenyl)piperazin-1-yl moiety 179
4-Sulfamoylphenylalkylamides as Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae 179
3D Pharmacophore model and synthesys of NMDA receptor subunit NR2B antagonists 178
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 178
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 178
Design and optimization of isoquinoline-sulfonamides as potent and selective inhibitors of human carbonic anhydrase VII 177
Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms 177
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis 176
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 175
Synthesis and biochemical evaluation of 5-(pyridin-4-yl)-4H-1,2,4-triazol-4-amine-based inhibitors of tyrosinase from Agaricus bisporus 174
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 170
A new potential approach to block HIV-1 replication via protein–protein interaction and strand-transfer inhibition 170
Anti-HIV agents: design and discovery of new potent RT inhibitors 169
Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson’s disease 169
Vitamin D: a steroid hormone with progesterone-like activity 165
Merging lithium carbenoid homologation and enzymatic reduction: A combinative approach to the HIV-protease inhibitor Nelfinavir 165
P158-DEVELOPMENT OF FLEXIBLE ARYLSULFONAMIDES AS POTENTIAL MULTITARGET ANTICANCER AGENTS 165
Analysis of structure-activity relationships in a series of 4-(1-piperazinyl)phenol-based derivatives as competitive inhibitors of Tyrosinase 165
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 164
6-Chloro-1-(3,5-dimethylphenylsulfonyl)-1H-benzimidazol-2(3H)-one 164
Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(4 '-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline AMPAR antagonists 163
Antiretroviral strategy using multi-target agents 162
HIV-1 integrase strand-transfer inhibitors: Design, synthesis and molecular modeling investigation 162
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 161
DISCOVERY OF NEW INDOLE DERIVATES AS NEUROPROTECTIVE AGENTS 161
Discovery of potent and selective inhibitors of druggable carbonic anhydrase isoforms 160
3D Pharmacophore Models for 1,2,3,4-Tetrahydroisoquinoline Derivatives Acting as Anticonvulsant Agents 160
In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae 160
Synthesis and biological evaluation of sulfonamide-based compounds as inhibitors of carbonic anhydrase from Vibrio cholerae 159
Combined ligand-based and target-based approach to design NR2B/NMDA receptor antagonists 159
Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor. 159
Identification of isoquinoline-sulfonamides as potent and selective carbonic anhydrase inhibitors 159
Modificazioni strutturali del gruppo dichetoacido (DKA) di potenti inibitori dell'Integrasi dell'HIV-1 158
Inhibitors of the Interactions between HIV-1 IN and the Cofactor LEDGF/p75 158
Graphene Quantum Dots Based Systems As HIV Inhibitors 157
In Silico Strategy for Targeting the mTOR Kinase at Rapamycin Binding Site by Small Molecules 157
Combined strategies for the discovery of ionotropic glutamate receptor antagonists 156
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 156
Evaluation of 4-(4-Fluorobenzyl)piperazin-1-yl]-Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects 156
2-Acetil-1-(4'-clorofenil)-6,7-dimetossi-1,2,3,4-tetraidroisochinolina (Ps3Ac) Potente AMPA-antagonista: Definizione del Profilo Enantiofarmacobiologico 155
Novel Potent Anticonvulsant Agent Containing a Tetrahydroisoquinoline Skeleton. 154
Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as Potent Carbonic Anhydrase Inhibitors: Synthesis, Biological Evaluation, and Enzyme−Ligand X-ray Studies 154
Analysis of the full-length integrase-DNA complex by a modified approach for DNA docking 153
Nuovi ligandi del recettore NR2B/NMDA a struttura indolica 152
Searching for indole derivatives as potential mushroom tyrosinase inhibitors 152
Design, synthesis and in vitro evaluation of 4-fluorobenzyl- and 4-hydroxyphenyl-based compounds targeting tyrosinases 152
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT 151
Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from Agaricus bisporus 150
Binding mode investigation and SAR studies of HIV-1 integrase inhibitors 150
Synthesis and anti-HIV activity of carboxylated and drug-conjugated multi-walled carbon nanotubes 149
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 149
From NMDA receptor antagonists to discovery of selective σ2 receptor ligands 149
Synthesis of new pyridazine derivatives as potential anti-HIV-1 agents 148
INVESTIGATION ON PYRIDINYL-1,2,4-TRIAZOLE-BASED COMPOUNDS AS -SYN AGGREGATION INHIBITORS FOR TREATING PARKINSON’S DISEASE 148
Binding modes of noncompetitive AMPA antagonists: a computational approach 147
Synthesis and structure-active relationship of 1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline anticonvulsants 147
Structural optimization and in vitro evaluation of new 1-(4-fluorobenzyl)piperazine derivatives as inhibitors of Tyrosinase from Agaricus bisporus 147
Antiretroviral strategy: design and synthesis of HIV-1 IN-LEDGF/p75 interaction inhibitors 146
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL’INTEGRASI DELL’HIV-1 145
Small Molecules Targeting Protein–Protein Interactions: A Promising Anti-HIV Strategy 145
Design and synthesis of 2,3-diaryl-1,3-thiazolidin-4one potent HIV-1 RT-inhibitors. 144
Probing the molecular interactions between the human Carbonic Anhydrases (hCAs) and a novel class of benzenesulfonamides 143
Serendipitous discovery of indole derivatives as potent tyrosinase inhibitors 142
Searching for alpha-syn inhibitors to fight Parkinson’s disease 142
Exploring the chemical space of 3-chloro-4-fluorophenyl-based compounds as tyrosinase inhibitors 140
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell'integrasi dell'HIV-1. 140
Ligand-Based Discovery of a Small Molecule as Inhibitor of α-Synuclein Amyloid Formation 139
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL'INTEGRASI DELL'HIV-1 138
Discovery of HIV-1 Integrase and cellular cofactor LEDGF/p75 interaction inhibitors 138
Discovery of potent HIV-1 integrase strand transfer inhibitors: design and synthetic strategies 138
Discovery and optimization of isoquinoline-derived inhibitors of human Carbonic Anhydrases (hCAs) 138
Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile 137
HIV-1 integrase strand-transfer inhibitors: design and synthetic strategies in the process of a lead optimization 137
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 136
Computational and synthetic approaches for the discovery of HIV-1 integrase inhibitors 136
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 135
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 135
Derivati benzimidazolonici ed analoghi come potenti inibitori non-nucleosidici dell'RT dell'HIV-1 135
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series 134
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis 134
Efficient 3D Database screening for novel HIV-1 IN inhibitors 134
Totale 20.807
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Categoria #
all - tutte 119.961
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 119.961
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021676 0 0 0 0 0 0 0 0 0 238 154 284
2021/20221.844 32 284 33 73 81 29 163 63 39 67 371 609
2022/20235.186 400 443 235 450 387 508 108 273 2.120 15 185 62
2023/20241.327 96 201 96 244 117 221 24 45 5 116 29 133
2024/20255.947 101 95 110 344 257 195 196 1.385 1.459 332 525 948
2025/202621.326 794 2.469 4.277 1.455 1.402 4.059 2.048 2.199 2.106 517 0 0
Totale 41.093