IRIS
DE LUCA, Laura
 Distribuzione geografica
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Continente #
NA - Nord America 17.347
EU - Europa 14.735
AS - Asia 7.294
SA - Sud America 2.582
Continente sconosciuto - Info sul continente non disponibili 411
AF - Africa 220
OC - Oceania 12
Totale 42.601
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Nazione #
US - Stati Uniti d'America 17.026
RU - Federazione Russa 7.836
SG - Singapore 3.089
BR - Brasile 2.224
CN - Cina 1.972
IE - Irlanda 1.738
SE - Svezia 1.439
IT - Italia 781
HK - Hong Kong 756
UA - Ucraina 707
DE - Germania 626
VN - Vietnam 556
FR - Francia 412
GB - Regno Unito 360
FI - Finlandia 359
IN - India 258
CA - Canada 143
AR - Argentina 131
BD - Bangladesh 106
MX - Messico 97
PL - Polonia 85
CZ - Repubblica Ceca 74
IQ - Iraq 68
TR - Turchia 67
JP - Giappone 59
ZA - Sudafrica 59
EC - Ecuador 56
BE - Belgio 54
NL - Olanda 47
MA - Marocco 46
AT - Austria 45
ES - Italia 45
UZ - Uzbekistan 44
ID - Indonesia 38
VE - Venezuela 36
PK - Pakistan 35
CO - Colombia 34
CI - Costa d'Avorio 26
CL - Cile 26
PY - Paraguay 25
SA - Arabia Saudita 23
KE - Kenya 22
AE - Emirati Arabi Uniti 21
EG - Egitto 21
JO - Giordania 18
PE - Perù 18
UY - Uruguay 17
AZ - Azerbaigian 16
JM - Giamaica 16
GR - Grecia 15
PH - Filippine 15
IR - Iran 14
NP - Nepal 14
BO - Bolivia 13
MY - Malesia 13
NO - Norvegia 13
HN - Honduras 12
LV - Lettonia 12
OM - Oman 12
KG - Kirghizistan 11
PA - Panama 11
PS - Palestinian Territory 11
DO - Repubblica Dominicana 10
DZ - Algeria 10
IL - Israele 10
KZ - Kazakistan 10
RO - Romania 10
AL - Albania 9
CR - Costa Rica 9
LK - Sri Lanka 9
LT - Lituania 9
TN - Tunisia 8
CH - Svizzera 7
PT - Portogallo 7
SK - Slovacchia (Repubblica Slovacca) 7
AU - Australia 6
LB - Libano 6
RS - Serbia 6
AM - Armenia 5
EE - Estonia 5
GT - Guatemala 5
KR - Corea 5
MD - Moldavia 5
NZ - Nuova Zelanda 5
SN - Senegal 5
SY - Repubblica araba siriana 5
TT - Trinidad e Tobago 5
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AO - Angola 4
BY - Bielorussia 4
ET - Etiopia 4
GE - Georgia 4
HU - Ungheria 4
NI - Nicaragua 4
TH - Thailandia 4
TW - Taiwan 4
BG - Bulgaria 3
BH - Bahrain 3
GA - Gabon 3
Totale 42.151
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Città #
Dallas 5.579
Moscow 2.251
Dublin 1.735
Singapore 1.652
Ashburn 1.618
Jacksonville 1.328
Chandler 1.321
Nyköping 945
Hong Kong 753
Beijing 718
San Jose 536
Council Bluffs 468
The Dalles 336
Los Angeles 334
Princeton 296
Medford 258
Cambridge 256
Dearborn 256
Lauterbourg 252
Des Moines 229
Messina 228
Dong Ket 186
Boardman 170
Ann Arbor 158
São Paulo 150
Buffalo 135
Ho Chi Minh City 124
Munich 117
New York 111
Hyderabad 87
Guangzhou 86
Wilmington 82
Woodbridge 80
Tianjin 78
Orem 74
Hanoi 72
Lancaster 69
Redondo Beach 69
Santa Clara 69
Belo Horizonte 65
Warsaw 64
Pune 60
Columbus 58
Jinan 58
Turku 57
Brno 56
Rio de Janeiro 54
Frankfurt am Main 53
Brooklyn 52
San Mateo 52
Shenyang 51
Brussels 49
Chicago 48
Tokyo 48
Brasília 47
Milan 47
Nanjing 46
Denver 45
Catania 44
London 44
Montreal 44
Seattle 43
Tashkent 42
Atlanta 41
Phoenix 41
Johannesburg 37
Houston 35
Shanghai 35
Haikou 33
Lappeenranta 33
Vienna 33
Nuremberg 31
Curitiba 29
Hebei 29
Manchester 29
Baghdad 28
Chennai 28
Stockholm 27
Taizhou 27
Abidjan 26
Hangzhou 25
San Francisco 25
Shenzhen 25
Goiânia 24
Mexico City 24
Rome 24
Amsterdam 23
Toronto 23
Zhengzhou 23
Da Nang 22
Poplar 22
Washington 22
Campinas 21
Guarulhos 21
Guayaquil 21
Ningbo 21
Porto Alegre 21
Boston 20
Dhaka 20
Düsseldorf 20
Totale 25.482
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Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 4.616
1,3-THIAZOLIDIN-4-ONES:POTENT AND HIGHLY SELECTIVE ANTI-HIV-1 AGENTS 284
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 276
Chemical exploration of 4-(4-fluorobenzyl)piperidine fragment for the development of new tyrosinase inhibitors 259
Inhibition of HIV-1 RT activity by a new series of 3-(1,3,4-thiadiazol-2-yl)thiazolidin-4-one derivatives 234
1-Benzylpiperidine derivatives: design and synthesis of new compounds as tyrosinase inhibitors from Agaricus bisporus 227
4-Fluorobenzylpiperazine-Containing Derivatives as Efficient Inhibitors of Mushroom Tyrosinase 218
Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases 207
AMPA receptor antagonists: Synthesis and pharmacological evaluation 205
Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile 204
2-Hydroxyisoquinoline-1,3(2H,4H)-diones as inhibitors of HIV-1 integrase and reverse transcriptase RNase H domain: Influence of the alkylation of position 4 203
Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments 203
Anticonvulsant agent: enhancement of physicochemical properties 202
Computational methods to analyze and predict the binding mode of inhibitors targeting both human and mushroom tyrosinase 194
A Combination of Pharmacophore and Docking-based Virtual Screening to Discover new Tyrosinase Inhibitors 193
Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives 192
P158-DEVELOPMENT OF FLEXIBLE ARYLSULFONAMIDES AS POTENTIAL MULTITARGET ANTICANCER AGENTS 192
4-[1-(4-Fluorobenzyl)-4-hydroxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid as a prototype to develop dual inhibitors of HIV-1 integration process. 191
Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety 190
Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms 190
InVivo Evaluation of Selective Carbonic Anhydrase Inhibitors as Potential Anticonvulsant Agents 187
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 186
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis 185
3D Pharmacophore model and synthesys of NMDA receptor subunit NR2B antagonists 184
Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms 184
Design and optimization of isoquinoline-sulfonamides as potent and selective inhibitors of human carbonic anhydrase VII 183
Discovery of a new potent inhibitor of mushroom tyrosinase (Agaricus bisporus) containing 4-(4-hydroxyphenyl)piperazin-1-yl moiety 183
4-Sulfamoylphenylalkylamides as Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae 183
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 182
Synthesis and biochemical evaluation of 5-(pyridin-4-yl)-4H-1,2,4-triazol-4-amine-based inhibitors of tyrosinase from Agaricus bisporus 178
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 176
Anti-HIV agents: design and discovery of new potent RT inhibitors 175
A new potential approach to block HIV-1 replication via protein–protein interaction and strand-transfer inhibition 173
Vitamin D: a steroid hormone with progesterone-like activity 173
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 172
6-Chloro-1-(3,5-dimethylphenylsulfonyl)-1H-benzimidazol-2(3H)-one 172
Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson’s disease 172
Merging lithium carbenoid homologation and enzymatic reduction: A combinative approach to the HIV-protease inhibitor Nelfinavir 171
Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(4 '-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline AMPAR antagonists 170
HIV-1 integrase strand-transfer inhibitors: Design, synthesis and molecular modeling investigation 170
In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae 168
Analysis of structure-activity relationships in a series of 4-(1-piperazinyl)phenol-based derivatives as competitive inhibitors of Tyrosinase 167
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 166
Antiretroviral strategy using multi-target agents 166
3D Pharmacophore Models for 1,2,3,4-Tetrahydroisoquinoline Derivatives Acting as Anticonvulsant Agents 166
Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor. 164
Identification of isoquinoline-sulfonamides as potent and selective carbonic anhydrase inhibitors 164
DISCOVERY OF NEW INDOLE DERIVATES AS NEUROPROTECTIVE AGENTS 164
Synthesis and biological evaluation of sulfonamide-based compounds as inhibitors of carbonic anhydrase from Vibrio cholerae 163
Graphene Quantum Dots Based Systems As HIV Inhibitors 163
In Silico Strategy for Targeting the mTOR Kinase at Rapamycin Binding Site by Small Molecules 163
Evaluation of 4-(4-Fluorobenzyl)piperazin-1-yl]-Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects 163
Combined strategies for the discovery of ionotropic glutamate receptor antagonists 162
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 162
Discovery of potent and selective inhibitors of druggable carbonic anhydrase isoforms 162
Inhibitors of the Interactions between HIV-1 IN and the Cofactor LEDGF/p75 162
2-Acetil-1-(4'-clorofenil)-6,7-dimetossi-1,2,3,4-tetraidroisochinolina (Ps3Ac) Potente AMPA-antagonista: Definizione del Profilo Enantiofarmacobiologico 161
Combined ligand-based and target-based approach to design NR2B/NMDA receptor antagonists 160
Analysis of the full-length integrase-DNA complex by a modified approach for DNA docking 159
Modificazioni strutturali del gruppo dichetoacido (DKA) di potenti inibitori dell'Integrasi dell'HIV-1 159
Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as Potent Carbonic Anhydrase Inhibitors: Synthesis, Biological Evaluation, and Enzyme−Ligand X-ray Studies 159
Design, synthesis and in vitro evaluation of 4-fluorobenzyl- and 4-hydroxyphenyl-based compounds targeting tyrosinases 159
Novel Potent Anticonvulsant Agent Containing a Tetrahydroisoquinoline Skeleton. 158
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 158
Synthesis and anti-HIV activity of carboxylated and drug-conjugated multi-walled carbon nanotubes 157
From NMDA receptor antagonists to discovery of selective σ2 receptor ligands 157
Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from Agaricus bisporus 156
Binding modes of noncompetitive AMPA antagonists: a computational approach 156
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 155
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT 155
Antiretroviral strategy: design and synthesis of HIV-1 IN-LEDGF/p75 interaction inhibitors 155
Searching for indole derivatives as potential mushroom tyrosinase inhibitors 155
Nuovi ligandi del recettore NR2B/NMDA a struttura indolica 154
Synthesis and structure-active relationship of 1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline anticonvulsants 152
Binding mode investigation and SAR studies of HIV-1 integrase inhibitors 152
Synthesis of new pyridazine derivatives as potential anti-HIV-1 agents 150
INVESTIGATION ON PYRIDINYL-1,2,4-TRIAZOLE-BASED COMPOUNDS AS -SYN AGGREGATION INHIBITORS FOR TREATING PARKINSON’S DISEASE 150
Structural optimization and in vitro evaluation of new 1-(4-fluorobenzyl)piperazine derivatives as inhibitors of Tyrosinase from Agaricus bisporus 149
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL’INTEGRASI DELL’HIV-1 148
Small Molecules Targeting Protein–Protein Interactions: A Promising Anti-HIV Strategy 148
Design and synthesis of 2,3-diaryl-1,3-thiazolidin-4one potent HIV-1 RT-inhibitors. 147
Probing the molecular interactions between the human Carbonic Anhydrases (hCAs) and a novel class of benzenesulfonamides 147
Serendipitous discovery of indole derivatives as potent tyrosinase inhibitors 145
Searching for alpha-syn inhibitors to fight Parkinson’s disease 145
Exploring the chemical space of 3-chloro-4-fluorophenyl-based compounds as tyrosinase inhibitors 144
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis 144
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell'integrasi dell'HIV-1. 144
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 144
Ligand-Based Discovery of a Small Molecule as Inhibitor of α-Synuclein Amyloid Formation 143
Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile 142
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL'INTEGRASI DELL'HIV-1 141
Discovery and optimization of isoquinoline-derived inhibitors of human Carbonic Anhydrases (hCAs) 141
Computational and synthetic approaches for the discovery of HIV-1 integrase inhibitors 140
Discovery of HIV-1 Integrase and cellular cofactor LEDGF/p75 interaction inhibitors 140
Discovery of potent HIV-1 integrase strand transfer inhibitors: design and synthetic strategies 140
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 139
HIV-1 integrase strand-transfer inhibitors: design and synthetic strategies in the process of a lead optimization 139
The 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors 139
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 138
Derivati benzimidazolonici ed analoghi come potenti inibitori non-nucleosidici dell'RT dell'HIV-1 138
Totale 21.426
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Categoria #
all - tutte 131.909
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 131.909
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.812 0 284 33 73 81 29 163 63 39 67 371 609
2022/20235.186 400 443 235 450 387 508 108 273 2.120 15 185 62
2023/20241.327 96 201 96 244 117 221 24 45 5 116 29 133
2024/20255.947 101 95 110 344 257 195 196 1.385 1.459 332 525 948
2025/202622.003 794 2.469 4.277 1.455 1.402 4.059 2.048 2.199 2.106 679 261 254
2026/2027831 257 574 0 0 0 0 0 0 0 0 0 0
Totale 42.601