IRIS
DE LUCA, Laura
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 16.577
EU - Europa 14.704
AS - Asia 7.250
SA - Sud America 2.562
AF - Africa 219
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 10
Totale 41.334
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 16.298
RU - Federazione Russa 7.836
SG - Singapore 3.083
BR - Brasile 2.214
CN - Cina 1.946
IE - Irlanda 1.738
SE - Svezia 1.439
IT - Italia 766
HK - Hong Kong 755
UA - Ucraina 706
DE - Germania 626
VN - Vietnam 553
FR - Francia 408
GB - Regno Unito 360
FI - Finlandia 359
IN - India 258
AR - Argentina 127
CA - Canada 127
BD - Bangladesh 102
MX - Messico 93
PL - Polonia 85
CZ - Repubblica Ceca 74
IQ - Iraq 68
TR - Turchia 67
JP - Giappone 59
ZA - Sudafrica 59
EC - Ecuador 55
BE - Belgio 54
NL - Olanda 47
MA - Marocco 46
AT - Austria 45
UZ - Uzbekistan 44
ES - Italia 37
ID - Indonesia 37
VE - Venezuela 36
PK - Pakistan 35
CO - Colombia 32
CI - Costa d'Avorio 26
CL - Cile 25
PY - Paraguay 25
SA - Arabia Saudita 23
KE - Kenya 22
EG - Egitto 21
AE - Emirati Arabi Uniti 19
JO - Giordania 18
PE - Perù 17
UY - Uruguay 17
AZ - Azerbaigian 16
GR - Grecia 15
PH - Filippine 15
IR - Iran 14
NP - Nepal 14
NO - Norvegia 13
BO - Bolivia 12
LV - Lettonia 12
MY - Malesia 12
OM - Oman 12
KG - Kirghizistan 11
PS - Palestinian Territory 11
DO - Repubblica Dominicana 10
IL - Israele 10
KZ - Kazakistan 10
PA - Panama 10
RO - Romania 10
AL - Albania 9
DZ - Algeria 9
JM - Giamaica 9
LK - Sri Lanka 9
HN - Honduras 8
LT - Lituania 8
TN - Tunisia 8
PT - Portogallo 7
SK - Slovacchia (Repubblica Slovacca) 7
AU - Australia 6
CH - Svizzera 6
LB - Libano 6
RS - Serbia 6
AM - Armenia 5
CR - Costa Rica 5
EE - Estonia 5
GT - Guatemala 5
KR - Corea 5
MD - Moldavia 5
NZ - Nuova Zelanda 5
SN - Senegal 5
SY - Repubblica araba siriana 5
XK - ???statistics.table.value.countryCode.XK??? 5
A2 - ???statistics.table.value.countryCode.A2??? 4
AO - Angola 4
ET - Etiopia 4
GE - Georgia 4
HU - Ungheria 4
NI - Nicaragua 4
TH - Thailandia 4
TT - Trinidad e Tobago 4
TW - Taiwan 4
BG - Bulgaria 3
BH - Bahrain 3
BY - Bielorussia 3
GA - Gabon 3
Totale 41.290
Salva come PNG Salva come JPEG
Città #
Dallas 5.578
Moscow 2.251
Dublin 1.735
Singapore 1.647
Ashburn 1.596
Jacksonville 1.327
Chandler 1.321
Nyköping 945
Hong Kong 752
Beijing 712
San Jose 517
The Dalles 335
Los Angeles 333
Princeton 296
Medford 257
Cambridge 256
Dearborn 256
Lauterbourg 252
Des Moines 229
Messina 228
Dong Ket 186
Boardman 170
Ann Arbor 158
São Paulo 149
Buffalo 135
Ho Chi Minh City 124
Munich 117
New York 110
Council Bluffs 106
Hyderabad 87
Guangzhou 86
Wilmington 82
Woodbridge 79
Tianjin 78
Orem 74
Hanoi 71
Lancaster 69
Redondo Beach 69
Belo Horizonte 65
Warsaw 64
Pune 60
Jinan 58
Turku 57
Brno 56
Santa Clara 56
Rio de Janeiro 54
Frankfurt am Main 53
San Mateo 52
Shenyang 51
Brussels 49
Tokyo 48
Brasília 47
Brooklyn 47
Chicago 46
Nanjing 46
Milan 45
Denver 44
London 44
Catania 43
Seattle 43
Tashkent 42
Montreal 41
Phoenix 39
Johannesburg 37
Atlanta 36
Shanghai 35
Haikou 33
Houston 33
Lappeenranta 33
Vienna 33
Nuremberg 31
Curitiba 29
Hebei 29
Manchester 29
Baghdad 28
Chennai 28
Stockholm 27
Taizhou 27
Abidjan 26
Hangzhou 25
San Francisco 25
Shenzhen 25
Goiânia 24
Rome 24
Amsterdam 23
Mexico City 23
Toronto 23
Zhengzhou 23
Poplar 22
Campinas 21
Da Nang 21
Guarulhos 21
Ningbo 21
Porto Alegre 21
Washington 21
Boston 20
Dhaka 20
Düsseldorf 20
Francofonte 20
Guayaquil 20
Totale 24.980
Salva come PNG Salva come JPEG
Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 4.608
1,3-THIAZOLIDIN-4-ONES:POTENT AND HIGHLY SELECTIVE ANTI-HIV-1 AGENTS 280
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 271
Chemical exploration of 4-(4-fluorobenzyl)piperidine fragment for the development of new tyrosinase inhibitors 256
1-Benzylpiperidine derivatives: design and synthesis of new compounds as tyrosinase inhibitors from Agaricus bisporus 222
4-Fluorobenzylpiperazine-Containing Derivatives as Efficient Inhibitors of Mushroom Tyrosinase 216
Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases 203
AMPA receptor antagonists: Synthesis and pharmacological evaluation 203
Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile 200
Anticonvulsant agent: enhancement of physicochemical properties 199
Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments 198
2-Hydroxyisoquinoline-1,3(2H,4H)-diones as inhibitors of HIV-1 integrase and reverse transcriptase RNase H domain: Influence of the alkylation of position 4 196
4-[1-(4-Fluorobenzyl)-4-hydroxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid as a prototype to develop dual inhibitors of HIV-1 integration process. 190
Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives 190
A Combination of Pharmacophore and Docking-based Virtual Screening to Discover new Tyrosinase Inhibitors 190
P158-DEVELOPMENT OF FLEXIBLE ARYLSULFONAMIDES AS POTENTIAL MULTITARGET ANTICANCER AGENTS 190
Computational methods to analyze and predict the binding mode of inhibitors targeting both human and mushroom tyrosinase 188
Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety 188
Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms 186
3D Pharmacophore model and synthesys of NMDA receptor subunit NR2B antagonists 183
InVivo Evaluation of Selective Carbonic Anhydrase Inhibitors as Potential Anticonvulsant Agents 182
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 181
Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms 181
Discovery of a new potent inhibitor of mushroom tyrosinase (Agaricus bisporus) containing 4-(4-hydroxyphenyl)piperazin-1-yl moiety 181
4-Sulfamoylphenylalkylamides as Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae 180
Design and optimization of isoquinoline-sulfonamides as potent and selective inhibitors of human carbonic anhydrase VII 179
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis 179
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 178
Synthesis and biochemical evaluation of 5-(pyridin-4-yl)-4H-1,2,4-triazol-4-amine-based inhibitors of tyrosinase from Agaricus bisporus 176
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 175
Anti-HIV agents: design and discovery of new potent RT inhibitors 172
A new potential approach to block HIV-1 replication via protein–protein interaction and strand-transfer inhibition 172
Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson’s disease 172
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 171
Vitamin D: a steroid hormone with progesterone-like activity 170
Merging lithium carbenoid homologation and enzymatic reduction: A combinative approach to the HIV-protease inhibitor Nelfinavir 169
6-Chloro-1-(3,5-dimethylphenylsulfonyl)-1H-benzimidazol-2(3H)-one 168
Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(4 '-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline AMPAR antagonists 167
HIV-1 integrase strand-transfer inhibitors: Design, synthesis and molecular modeling investigation 166
Analysis of structure-activity relationships in a series of 4-(1-piperazinyl)phenol-based derivatives as competitive inhibitors of Tyrosinase 166
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 165
In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae 165
Antiretroviral strategy using multi-target agents 164
3D Pharmacophore Models for 1,2,3,4-Tetrahydroisoquinoline Derivatives Acting as Anticonvulsant Agents 164
Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor. 162
Combined strategies for the discovery of ionotropic glutamate receptor antagonists 161
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 161
DISCOVERY OF NEW INDOLE DERIVATES AS NEUROPROTECTIVE AGENTS 161
Graphene Quantum Dots Based Systems As HIV Inhibitors 161
Synthesis and biological evaluation of sulfonamide-based compounds as inhibitors of carbonic anhydrase from Vibrio cholerae 160
Discovery of potent and selective inhibitors of druggable carbonic anhydrase isoforms 160
Identification of isoquinoline-sulfonamides as potent and selective carbonic anhydrase inhibitors 160
Inhibitors of the Interactions between HIV-1 IN and the Cofactor LEDGF/p75 160
2-Acetil-1-(4'-clorofenil)-6,7-dimetossi-1,2,3,4-tetraidroisochinolina (Ps3Ac) Potente AMPA-antagonista: Definizione del Profilo Enantiofarmacobiologico 160
Evaluation of 4-(4-Fluorobenzyl)piperazin-1-yl]-Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects 160
Combined ligand-based and target-based approach to design NR2B/NMDA receptor antagonists 159
Modificazioni strutturali del gruppo dichetoacido (DKA) di potenti inibitori dell'Integrasi dell'HIV-1 158
Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as Potent Carbonic Anhydrase Inhibitors: Synthesis, Biological Evaluation, and Enzyme−Ligand X-ray Studies 158
In Silico Strategy for Targeting the mTOR Kinase at Rapamycin Binding Site by Small Molecules 158
Novel Potent Anticonvulsant Agent Containing a Tetrahydroisoquinoline Skeleton. 157
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 157
Design, synthesis and in vitro evaluation of 4-fluorobenzyl- and 4-hydroxyphenyl-based compounds targeting tyrosinases 157
Analysis of the full-length integrase-DNA complex by a modified approach for DNA docking 156
Synthesis and anti-HIV activity of carboxylated and drug-conjugated multi-walled carbon nanotubes 155
Searching for indole derivatives as potential mushroom tyrosinase inhibitors 154
Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from Agaricus bisporus 153
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT 153
Nuovi ligandi del recettore NR2B/NMDA a struttura indolica 153
From NMDA receptor antagonists to discovery of selective σ2 receptor ligands 153
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 152
Antiretroviral strategy: design and synthesis of HIV-1 IN-LEDGF/p75 interaction inhibitors 152
Binding modes of noncompetitive AMPA antagonists: a computational approach 151
Binding mode investigation and SAR studies of HIV-1 integrase inhibitors 151
Synthesis and structure-active relationship of 1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline anticonvulsants 150
Synthesis of new pyridazine derivatives as potential anti-HIV-1 agents 148
Structural optimization and in vitro evaluation of new 1-(4-fluorobenzyl)piperazine derivatives as inhibitors of Tyrosinase from Agaricus bisporus 148
INVESTIGATION ON PYRIDINYL-1,2,4-TRIAZOLE-BASED COMPOUNDS AS -SYN AGGREGATION INHIBITORS FOR TREATING PARKINSON’S DISEASE 148
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL’INTEGRASI DELL’HIV-1 147
Small Molecules Targeting Protein–Protein Interactions: A Promising Anti-HIV Strategy 146
Design and synthesis of 2,3-diaryl-1,3-thiazolidin-4one potent HIV-1 RT-inhibitors. 145
Probing the molecular interactions between the human Carbonic Anhydrases (hCAs) and a novel class of benzenesulfonamides 144
Serendipitous discovery of indole derivatives as potent tyrosinase inhibitors 143
Searching for alpha-syn inhibitors to fight Parkinson’s disease 143
Ligand-Based Discovery of a Small Molecule as Inhibitor of α-Synuclein Amyloid Formation 142
Exploring the chemical space of 3-chloro-4-fluorophenyl-based compounds as tyrosinase inhibitors 142
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell'integrasi dell'HIV-1. 141
PROGETTAZIONE E SINTESI DI NUOVI DKA ANALOGHI COME POTENZIALI INIBITORI DELL'INTEGRASI DELL'HIV-1 140
Computational and synthetic approaches for the discovery of HIV-1 integrase inhibitors 139
Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile 139
Discovery of HIV-1 Integrase and cellular cofactor LEDGF/p75 interaction inhibitors 139
Discovery of potent HIV-1 integrase strand transfer inhibitors: design and synthetic strategies 139
Discovery and optimization of isoquinoline-derived inhibitors of human Carbonic Anhydrases (hCAs) 139
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis 138
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 137
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 137
HIV-1 integrase strand-transfer inhibitors: design and synthetic strategies in the process of a lead optimization 137
NOVEL N1-ARYL-2- ARYLTHIOACETAMIDOBENZIMIDAZOLES WERE EFFECTIVE AGAINST HERPES SIMPLEX VIRUS 1 (HSV-1) REPLICATION IN VITRO 137
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 136
Derivati benzimidazolonici ed analoghi come potenti inibitori non-nucleosidici dell'RT dell'HIV-1 136
Insight into the INSTIs binding mode: molecular modeling investigation and SAR studies 136
Totale 21.069
Salva come PNG Salva come JPEG
Categoria #
all - tutte 126.660
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 126.660
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021284 0 0 0 0 0 0 0 0 0 0 0 284
2021/20221.844 32 284 33 73 81 29 163 63 39 67 371 609
2022/20235.186 400 443 235 450 387 508 108 273 2.120 15 185 62
2023/20241.327 96 201 96 244 117 221 24 45 5 116 29 133
2024/20255.947 101 95 110 344 257 195 196 1.385 1.459 332 525 948
2025/202621.966 794 2.469 4.277 1.455 1.402 4.059 2.048 2.199 2.106 679 261 217
Totale 41.733